Results 181 to 190 of about 10,771,371 (375)

BAG2 Inhibits Cervical Cancer Progression by Modulating Type I Interferon Signaling through Stabilizing STING

Advanced Science, EarlyView.
Based on IP‐MS analysis, BAG2 is confirmed to be essential for ubiquitination and protein homeostasis regulation of STING in cervical cancer. BAG2 inhibits the ubiquitination and degradation of STING by forming a complex with STUB1, thereby activating the type I IFN signaling pathway and inhibiting the development of cervical cancer.
Shijie Yao, Siming Chen, Anjin Wang, Ziyan Liang, Xuelian Liu, Yang Gao, Hongbing Cai   +6 more
wiley   +1 more source

CD133+/ABCC5+ cervical cancer cells exhibit cancer stem cell properties

Heliyon
Objective: This study explores the correlation between Forkhead box M1 (FOXM1) and ATP-binding cassette subfamily C member 5 (ABCC5) in relation to paclitaxel resistance in cervical cancer. It aims to identify potential cervical cancer stem cell markers,
Lin He, Hengjun Qian, Ayinuer seyiti, Chengshaoxiong Yang, Ning Shi, Chen Chen, Pingxu Zhang, Youxiang Hou   +7 more
doaj  

Electron Microscope Studies of HeLa Cells Infected with Herpes Virus

, 1958
M. G. P. Stoker, Kevin M. Smith, R. W. Ross   +2 more
openalex   +1 more source

A SIMPLE AND RAPID METHOD FOR THE ISOLATION OF ENZYMATICALLY ACTIVE HELA CELL NUCLEI [PDF]

, 1969
Daniel Berkowitz, Tsuyoshi Kakefuda, Michael B. Sporn   +2 more
openalex   +1 more source

CircTP53/USP10/p53 signaling Axis as a Novel Regulator of Progression and Prognosis of Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
The study identifies a novel circular RNA derived from the TP53 gene (circTP53), which is upregulated in HNSCC and correlates with poor patient prognosis. It demonstrates that circTP53 promotes HNSCC progression by interacting with USP10, stabilizing both proteins, enhancing deubiquitination of p53, and thereby influencing tumor growth, with its ...
Yin Wang, Fen Chang, Zinan Li, Chengcheng Duan, Xiangkai Sun, Siyu Wang, Dongmin Wei, Wenming Li, Ye Qian, Shengda Cao, Juan Zhao, Dapeng Lei   +11 more
wiley   +1 more source

STUDIES ON THE EFFECTS OF ACTINOMYCETES PRODUCTS ON THE CULTURE OF HUMAN CARCINOMA CELLS (STRAIN HELA) I. THE EFFECT OF KNOWN ANTIBIOTICS HAVING NO OR SLIGHT TUMOR-INHIBITORY ACTIVITY ON HELA CELLS

, 1957
Kazuo Nitta
openalex   +2 more sources

Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase

Advanced Science, EarlyView.
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Lin Guo, Jiechun Lin, Qiwen Ren, Hao Sun, Yanhua Wu, Haofei Ge, Xiaolan Wu, Lihui Lin, Lining Liang, Changpeng Li, He Liu, Yuangbang Mai, Shilong Chu, Jiadong Liu, Jing Liu, Jiekai Chen, Duanqing Pei, Hui Zheng   +17 more
wiley   +1 more source

The effect of HeLa cell cytoplasm on the rate of sedimentation of RNA. [PDF]

, 1966
Marc Girard, David Baltimore
openalex   +1 more source

Biosecurity Primitive: Polymerase X‐based Genetic Physical Unclonable Functions

Advanced Science, EarlyView.
What if every cell line can carry an unforgeable genomic fingerprint—one that proves its origin, ensures its authenticity, and thwarts unauthorized duplication? Here, CRISPR‐induced DNA lesions paired with TdT‐mediated repair produce robust, unique, and unclonable genetic signatures—advancing the concept of molecular Physical Unclonable Functions (PUF)
Zikun Zhou, Taek Kang, Jie Chen, Yesh Doctor, Jocelyn G Camposagrado, Yiorgos Makris, Alexander Pertsemlidis, Leonidas Bleris   +7 more
wiley   +1 more source

Regulation of KLRC and Ceacam gene expression by miR-141 supports cell proliferation and metastasis in cervical cancer cells

BMC Cancer
Introduction MicroRNAs (miRNAs) are single RNA molecules that act as global regulators of gene expression in mammalian cells and thus constitute attractive targets in treating cancer.
Emad Dabous, Mai Alalem, Ahmed M. Awad, Khaled A. Elawdan, Ahmed M. Tabl, Shorouk Elsaka, Walid Said, Adel A. Guirgis, Hany Khalil   +8 more
doaj   +1 more source