Results 11 to 20 of about 256,219 (295)
Open Life Sciences, 2021 Adriamycin (ADR) is an important chemotherapy agent in many advanced cancers, but the emergence of drug resistance during treatment is a major limitation to its successful use.
Qi Min, Xie Lijuan, Duan Guihua
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Effects of TMCO1 on proliferation and migration of cervical cancer cells [PDF]
Zhongguo aizheng zazhiBackground and purpose: Transmembrane and coiled-coil domains 1 (TMCO1) is a recently discovered endoplasmic reticulum calcium channel protein that has been found to be associated with the progression of various tumors, however, its role in cervical ...
CHEN Xun, ZHENG Zhenxia, RUAN Xueru
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Leukemia-associated gene MLAA-34 reduces arsenic trioxide-induced apoptosis in HeLa cells via activation of the Wnt/β-catenin signaling pathway. [PDF]
PLoS ONE, 2017 Our laboratory previously used the SEREX method in U937 cells and identified a novel leukemia-associated gene MLAA-34, a novel splice variant of CAB39L associated with acute monocytic leukemia, that exhibited anti-apoptotic activities in U937 cells ...
Pengyu Zhang +6 more
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Confirmation of Connexin45 Underlying Weak Gap Junctional Intercellular Coupling in HeLa Cells
Biomolecules, 2020 Gap junctions (GJs) are intercellular channels that connect adjacent cells electrically and metabolically. The iodide-yellow fluorescent protein (I-YFP) gap junctional intercellular communication (GJIC) assay is a recently developed method with high ...
Eun Ju Choi +3 more
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The effect of proflavine on HeLa cells [PDF]
Biochemical Journal, 1966 1. The effect of proflavine on the metabolism of RNA, DNA and protein of HeLa cells was studied. 2. The synthesis of RNA, DNA and protein was progressively inhibited by concentrations of proflavine up to 43mum. 3. There was no simple relationship between the degrees of inhibition of synthesis of RNA, DNA and protein by increasing concentrations of ...
J W, Watts, M A, Davis
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Altered ganglioside GD3 in HeLa cells might influence the cytotoxic abilities of NK cells
Taiwanese Journal of Obstetrics & Gynecology, 2012 Objective: Previously, we found that altered sialidases in HeLa cells in a natural killer-HeLa (NK-HeLa) coculture system contributed to the decreased cytotoxic ability of NK cells.
Wen-Chi Lee +7 more
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Nanomaterials, 2022 The study of the interaction of engineered nanoparticles, including quantum dots (QDs), with cellular constituents and the kinetics of their localization and transport, has provided new insights into their biological consequences in cancers and for the ...
Min Zhang +4 more
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Біологічні студії, 2022 Background. Various cationic polymers have been proposed for use as carriers of genetic materials in biotechnology and biomedicine. The poly(2-dimethylamino)ethyl-methacrylate (poly(DMAEMA)) demonstrated high transfection efficiency and low cytotoxicity ...
N. S. Finiuk +5 more
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HeLa cells up-regulate Beclin1/autophagy pathway to confer resistance to doxorubicin
Di-san junyi daxue xuebao, 2019 Objective To investigate the role of doxorubicin (DOX) in the induction of protective autophagy in HeLa cells and explore the possible mechanism of DOX resistance.
GUO Yanjun, WANG Shuwei
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Cells, 2023 Pyruvate kinase M (PKM) 2 was described to interact with the inositol 1,4,5-trisphosphate (IP3) receptor (IP3R) and suppress its activity. To further investigate the physiological importance of the PKM2:IP3R interaction, we developed and characterized ...
Fernanda O. Lemos +4 more
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