Results 201 to 210 of about 10,441,214 (290)
Immunogenicity of experimental trachoma vaccines in baboons: I. Experimental methods, and preliminary tests with vaccines prepared in chick embryos and in HeLa cells [PDF]
Leslie Collier, W. A. Blyth
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Autophagy‐Mediated Suppression of Tumor Growth by Food‐Grade Lipid Nanoparticles in Mice
This work reveals a novel extracellular nanoparticle transport and metabolic pathway. Following cellular uptake, Food‐grade lipid nanoparticles (FLNs) selectively fuse with lipid droplets (LDs) rather than lysosomes, driving LDs accumulation. This process activates autophagy through the AMPK‐mTOR‐ULK1 signaling axis, facilitating tumor progression ...
Chenglu Peng+10 more
wiley +1 more source
The propagation and growth characteristics of rinderpest virus in HeLa cells [PDF]
B. Ließ, W. Plowright
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Engineering Liquid Hierarchical Materials with DNA‐Programmed Spherical Nucleic Acids
Programmable spherical nucleic acids assembly strategies for constructing hierarchical structures through engineered DNA bond to form novel liquid‐like metal droplets. Abstract Inspired by nature, the orchestration of self‐assembling building blocks into hierarchical superstructures offers a transformative approach to functional materials design. While
Zeyu Chen+7 more
wiley +1 more source
Programming of Poliovirus Inhibition of Deoxyribonucleic Acid Synthesis in HeLa Cells [PDF]
W. W. Ackermann, Daniel Wahl
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The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu+17 more
wiley +1 more source
MRC is a live‐cell method enabling visualization of protein–protein interactions and biomolecular condensates. It supports multi‐protein colocalization, binding analysis, and programmable condensate manipulation, providing a versatile platform for studying dynamic cellular organization.
Lei Peng+8 more
wiley +1 more source
Mitigating Cell Cycle Effects in Multi‐Omics Data: Solutions and Analytical Frameworks
The study highlights the cell‐cycle effects on multi‐omics analysis attributed to varying cell cycle compositions across cell types. To minimize the influence, we propose RTD correction in CNV calling with a high S‐phase ratio, and phase comparison in chromatin accessibility, DNA methylation, and transcriptomics.
Rui Nie+7 more
wiley +1 more source