Results 211 to 220 of about 10,441,214 (290)

Chemigenetic Encoding of Fluorescent Dyes Enables High‐Fidelity and Wash‐Free Imaging of Proteins in Live Cells

open access: yesAdvanced Science, EarlyView.
This study develops a chemigenetic strategy that combines synthetic dyes with genetically encoded fluorescence for high‐fidelity, no‐wash protein imaging. By utilizing FRET between fluorescent proteins and Halo‐tag dyes, this system ensures that only target‐bound dyes fluoresce, effectively suppressing background signals and enhancing the signal‐to ...
Xuelian Zhou   +8 more
wiley   +1 more source

Developing a Personalized Cancer Nanovaccine Using Coxsackievirus‐Reprogrammed Cancer Cell Membranes for Enhanced Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
A personalized nanovaccine combining PLGA‐encapsulated heat‐inactivated CVB3 and membranes from CVB3‐infected breast cancer cells stimulates potent antitumor immunity. It reduces immunosuppressive markers, enhances immune activation, and improves survival in vivo.
Amirhossein Bahreyni   +6 more
wiley   +1 more source

The metabolism of basic proteins in HeLa cell nuclei.

open access: green, 1966
Judson W. Spalding   +2 more
openalex   +1 more source

Hyperspectral Fluorescence Imaging with a New Polarity‐Ultrasensitive Fluorescent Probe

open access: yesAdvanced Science, EarlyView.
Based on the critical role of the π‐spacer in determining wavelength sensitivity to microenvironmental polarity, a new fluorescent probe, Lipi‐PS is rationally developed, which exhibits the highest polarity‐sensitivity so far. Its integration with hyperspectral fluorescence imaging enables multiscale polarity mapping across cells, tissues, and ...
Ri Zhou   +7 more
wiley   +1 more source

Biomolecular Interaction Prediction: The Era of AI

open access: yesAdvanced Science, EarlyView.
This review offers a thorough examination of recent progress in deep learning for predicting biomolecular interactions, including those involving proteins, nucleic acids, and small molecules. It covers data processing strategies, representative model architectures, and evaluation metrics, while highlighting current methodological limitations.
Haoping Wang, Xiangjie Meng, Yang Zhang
wiley   +1 more source

Advanced Synthesis and Fabrication Strategies for 2D Mesoporous Carbon Materials in Energy Storage and Conversion

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
The rising demand for efficient energy systems has spotlighted 2D mesoporous carbon materials due to their high surface area, tunable porosity, and electrical conductivity. This article explores synthesis methods (template‐assisted, chemical vapor deposition), fabrication techniques (electrospinning, freeze‐drying), and applications in batteries ...
Pariksha Bishnoi   +5 more
wiley   +1 more source

MicroRNA‐214 is aberrantly expressed in cervical cancers and inhibits the growth of HeLa cells

open access: yesIUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2009
Zuozhen Yang   +7 more
semanticscholar   +1 more source

A General Strategy to Fine‐Tune Group 14 Rhodamines for Ultrahigh Signal‐to‐Noise Ratio Labeling In Vivo by Nano‐Aggregation

open access: yesAggregate, EarlyView.
Group 14 rhodamines are one of the most widely explored fluorogenic probes with high signal‐to‐noise ratio (SNR). We have boosted the SNR of group 14 rhodamines by nano‐aggregation via a novel strategy by manipulating their dynamic physical and chemical states for the first time. The ultrahigh SNR fluorescence imaging offers a fundamental understanding
Ning Wang   +5 more
wiley   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

open access: yesAggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy