Results 221 to 230 of about 10,441,214 (290)
CELL CYCLE EVENTS IN THE HYDROCORTISONE REGULATION OF ALKALINE PHOSPHATASE IN HELA S3 CELLS
Martin J. Griffin, Raphael Ber
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Herein, we report a quinolinium‐based fluorescent probe, PA‐2, for near‐infrared super‐resolution imaging of lysosomal dynamics. Building on this, we next introduce a novel approach leveraging a large multimodal model (LMM), an advanced artificial intelligence tool, for automated image interpretation.
Rui Chen+7 more
wiley +1 more source
Recognition of ribosomal RNA sites in DNA. II. The HeLa cell system.
Giuseppe Attardi+2 more
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Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz+2 more
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Deep Learning‐Assisted Coherent Raman Scattering Microscopy
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu+4 more
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High‐Throughput Nanorheology of Living Cells Powered by Supervised Machine Learning
Herein, atomic force microscopy (AFM) and machine learning are combined to determine the viscoelastic properties of living cells at the nanoscale. A universal regressor that predicts the viscoelastic properties of mammalian cells from AFM experiments is developed. The regressor predicts the viscoelastic parameters of two cell lines.
Jaime R. Tejedor, Ricardo Garcia
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Endogenously Triggered DNAzyme‐Based Nanostructures for Gene‐Combined Therapy
DNAzymes show great promise for gene regulation and therapeutic use via controlled release triggered by endogenous factors. This review summarizes recent advances in designing and constructing nanoscale platforms enabling endogenously triggered release of DNAzyme.
Theoneste Muyizere+4 more
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A stress‐responsive folding promotor was developed by conjugating metal‐binding ligands and a redox‐active disulfide. The oxidative strength of the bifunctional disulfide was enhanced by metal coordination, inhibiting protein misfolding and up‐regulating the oxidative folding capacity under metal stress.
Keita Mori+8 more
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Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo+2 more
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Mitochondria‐targeting water‐soluble probe mTAP exclusively reacts with mitochondrial abasic sites, enabling the manipulation of mitochondrial DNA levels under genotoxic stress. Abstract Mitochondrial DNA (mtDNA) encodes essential genes for mitochondrial and cellular functions and acts as a cell signaling molecule in innate immune and inflammatory ...
Anal Jana, Yu‐Hsuan Chen, Linlin Zhao
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