Results 41 to 50 of about 243 (207)

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

AXIAL TENSILE CAPACITY OF HELICAL PILES FROM FIELD TESTS AND NUMERICAL STUDY [PDF]

open access: yesPort Said Engineering Research Journal, 2017
Helical piles are used to support structures subjected to axial and lateral loads. The main object of the paper is to study the behavior of helical piles in cohesive and cohesionless soils using a full scale field testing.
Tarek Salem, Mohamed Hussein
doaj   +1 more source

Research on Lateral Bearing Behavior of Spliced Helical Piles with the SPH Method

open access: yesApplied Sciences, 2022
The length of a spliced pile is 2 m assembled from an original spiral pile using a connector. The whole pile is the structure of the upper straight pipe and the lower spiral.
Guofeng Ren   +6 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Efficiency of RCC piles with helical grooves subjected to axial and lateral loads in cohesionless soil

open access: yesCogent Engineering
This paper presents an experimental and numerical investigation of RCC (Reinforced Concrete) piles with helical grooves under axial and lateral loads in cohesionless soil.
Arun Kumar Y. M.   +2 more
doaj   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Laboratory Model Study on the Pile-Forming Mechanisms and Bearing Deformation Characteristics of CFA Piles

open access: yesAdvances in Civil Engineering, 2021
To study the pile-forming mechanism and bearing deformation characteristics of continuous flight auger (CFA) piles, a series of procedures, including helical drilling, pulling up/grouting, and inserting cage/pile forming, were simulated in clay-sand ...
Deliang Zhu   +4 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

Laboratory Investigation of the Behavior of Helical Piles under Monotonic Loading at Different Loading Speeds [PDF]

open access: yesمهندسی عمران شریف
Today, one of the primary challenges faced by geotechnical engineers in dealing with problematic soils is to choose a suitable improvement method that, in addition to strengthening the soil, does not cause harmful damage to the environment. Helical piles
Seyed Sajjad Hosseini   +2 more
doaj   +1 more source

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