Results 51 to 60 of about 1,010 (252)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
AXIAL TENSILE CAPACITY OF HELICAL PILES FROM FIELD TESTS AND NUMERICAL STUDY [PDF]
Port Said Engineering Research Journal, 2017 Helical piles are used to support structures subjected to axial and lateral loads. The main object of the paper is to study the behavior of helical piles in cohesive and cohesionless soils using a full scale field testing.
Tarek Salem, Mohamed Hussein
doaj +1 more source
Research on Lateral Bearing Behavior of Spliced Helical Piles with the SPH Method
Applied Sciences, 2022 The length of a spliced pile is 2 m assembled from an original spiral pile using a connector. The whole pile is the structure of the upper straight pipe and the lower spiral.
Guofeng Ren +6 more
doaj +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
A Machine Learning-Based Approach for Predicting Installation Torque of Helical Piles from SPT Data
BuildingsHelical piles are advantageous alternatives in constructions subjected to high tractions in their foundations, like transmission towers. Installation torque is a key parameter to define installation equipment and the final depth of the helical pile. This
Marcelo Saraiva Peres +2 more
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Settlement based load capacity curve for single helix helical pile in c - ϕ soil
Soils and Foundations, 2023 Helical piles are getting increasingly popular for lightweight engineering applications. Currently, the helical pile is mostly designed with torque capacity; however, it cannot explain the foundation's anticipated settlement.
Nur Mohammad Shuman +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Advances in Civil Engineering, 2021 To study the pile-forming mechanism and bearing deformation characteristics of continuous flight auger (CFA) piles, a series of procedures, including helical drilling, pulling up/grouting, and inserting cage/pile forming, were simulated in clay-sand ...
Deliang Zhu +4 more
doaj +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source