Results 331 to 340 of about 194,742 (384)

Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity. [PDF]

ACS Infect Dis
Muthu Ramalingam B, Oh HJ, Sears JD, Chen CH, Vala A, Liu S, Talbot KM, Hossain MA, Brown PJ, Houliston S, Garcia Perez J, Li F, Amare MG, Halfmann P, Smith JL, Hirsch AJ, Arrowsmith CH, Halabelian L, Vargason A, Couñago RM, Arnold JJ, Cameron CE, Moorman NJ, Heise MT, Willson TM.   +24 more
europepmc   +1 more source

ARABIDOPSIS HOMOLOG OF TRITHORAX1 impacts lateral root development by epigenetic regulation of targets involved in root system architecture

New Phytologist, Volume 247, Issue 5, Page 2180-2195, September 2025.
Summary Developmental processes are regulated at multiple levels, including the epigenetic level. Among the epigenetic factors, histone H3 lysine 4 (H3K4) methyltransferases contribute to active transcription of target genes, and here, we explored how the H3K4 methyltransferase ARABIDOPSIS HOMOLOG OF TRITHORAX1 (ATX1) affects Arabidopsis thaliana ...
Selene Napsucialy‐Mendivil, Héctor H. Torres‐Martínez, Gustavo Rodríguez‐Alonso, Diana Marcela Rivera‐Toro, Raúl Alvarez‐Venegas, Marco Adán Júarez‐Verdayes, Svetlana Shishkova, Joseph G. Dubrovsky   +7 more
wiley   +1 more source

Structural and functional characterization of human SLFN14. [PDF]

Nucleic Acids Res
Luo M, Jia X, Wang ZW, Yang JY, Wang W, Chen J, Ou JY, Feng JX, Yu B, Wang S, Huang L, Morgan NV, Deng K, Chen T, Zhang Q, Gao S.   +15 more
europepmc   +1 more source

RNA elements and their biotechnological applications in plants

New Phytologist, Volume 247, Issue 6, Page 2517-2537, September 2025.
Summary Engineering of plants for improved traits and efficient heterologous protein production can be achieved by modifying or introducing cis‐ or trans‐acting RNA elements. The function of these elements depends not only on their nucleotide sequence but also on their highly dynamic higher order structures.
Filip Lastovka, Hadrien Peyret, George P. Lomonossoff, Betty Y.‐W. Chung   +3 more
wiley   +1 more source

A Supramolecular Material for Controlling Kiwifruit Bacterial Canker. [PDF]

Adv Sci (Weinh)
Deng X, Bian Q, Zhou M, Xie L, Zhang J, Liu T, Zhang Y, Zhang L, Zhang J, Bai L.   +9 more
europepmc   +1 more source

RECQ4 restricts non‐interfering crossover formation to fine‐tune meiotic recombination rates in rice

Plant Biotechnology Journal, Volume 23, Issue 9, Page 3760-3769, September 2025.
Summary Crop breeding fundamentally depends on meiotic crossovers (COs) to reshuffle genetic material and integrate favourable alleles into elite cultivars. Recombination frequency is of paramount importance in this process. Higher recombination rates enhance the probability of breaking linkage drag and generating novel allelic combinations.
Yafei Li, Hanli You, Xinjie Cheng, Bingxin Wang, Yangzi Zhao, Jiawei Chen, Lei Cao, Minsi Wen, Yansong Zhang, Zhuoran Chen, Qiong Luo, Zhukuan Cheng   +11 more
wiley   +1 more source

Acclimation of Synechocystis sp. PCC 6803 to Alkaline pH Under Ambient Air

Physiologia Plantarum, Volume 177, Issue 5, September/October 2025.
ABSTRACT Cyanobacteria can thrive at a wide pH range from neutral up to pH 11 depending on the species. Even though cyanobacteria are alkaliphilic, only limited information on the metabolic acclimation to alkaline pH is available. In this study, we conducted a mass‐spectrometry‐based comparative proteomic analysis of Synechocystis sp. PCC 6803 grown in
Henna Mustila, Michal Hubáček, Dorota Muth‐Pawlak, Yagut Allahverdiyeva   +3 more
wiley   +1 more source

Compact Origins and Where to Find Them: ORC's Guide to Genome-Wide Licensing. [PDF]

Bioessays
Speck C, Reuter LM.
europepmc   +1 more source

Intracellular and Extracellular Vesicle miRNA Signatures in Human iPSC‐Derived Neural Stem Cells and Floor Plate Progenitors

The FASEB Journal, Volume 39, Issue 16, 31 August 2025.
Human induced pluripotent stem cells were differentiated into neural stem cells and floor plate progenitors of dopaminergic neurons, followed by microRNA profiling. While intracellular differences were limited, extracellular vesicle microRNAs showed 27 differentially expressed microRNAs and five consistently enriched across lineages.
Lilian Cruz, Frederico Moraes Ferreira, Camila Miranda Lopes‐Ramos, Zhiyun Wei, William T. Hendriks, H. A. Jinnah, Helder I. Nakaya, D. Cristopher Bragg, Anna M. Krichevsky, Xandra Owens Breakefield, Marilene Hohmuth Lopes   +10 more
wiley   +1 more source

Targeting DNA helicase CMG complex and NFκB2-driven drug-resistant transcriptional axis to effectively treat KRAS^G12D-mutated pancreatic cancer. [PDF]

Exp Hematol Oncol
Xiao J, Kim J, Park B, Baylink DJ, Kwon C, Tran V, Lee S, Codorniz K, Tan L, Moreno PL, Schill-Depew A, Mirshahidi S, De Semir D, Hanna D, Naqvi K, Cao H, Chen CS, Xiu J, Lenz HJ, Mirshahidi H, Reeves ME, Xu Y.   +21 more
europepmc   +1 more source