Results 161 to 170 of about 358,107 (405)

Mosaicism in Vacuolating Cytotoxin Alleles of Helicobacter pylori

open access: yesJournal of Biological Chemistry, 1995
Approximately 50% of Helicobacter pylori strains produce a cytotoxin, encoded by vacA, that induces vacuolation of eukaryotic cells. Analysis of a clinically isolated tox strain (Tx30a) indicated secretion of a 93-kDa product from a 3933-base pair vacA ...
J. Atherton   +5 more
semanticscholar   +1 more source

Citrus Flavonoids as Antimicrobials

open access: yesChemistry &Biodiversity, EarlyView.
Citrus flavonoids are powerful and versatile antimicrobials whose mechanism of action often involves disruption of the bacterial membrane, thereby minimizing antimicrobial resistance. This study provides a unified perspective. ABSTRACT Citrus flavonoids are highly bioactive compounds exerting numerous health benefits including anticancer, antioxidant ...
Rosaria Ciriminna   +6 more
wiley   +1 more source

Magnetic-Guided Flexible Origami Robot toward Long-Term Phototherapy of H. pylori in the Stomach [PDF]

open access: yesarXiv
Helicobacter pylori, a pervasive bacterial infection associated with gastrointestinal disorders such as gastritis, peptic ulcer disease, and gastric cancer, impacts approximately 50% of the global population. The efficacy of standard clinical eradication therapies is diminishing due to the rise of antibiotic-resistant strains, necessitating alternative
arxiv  

Combination of gastric atrophy, reflux symptoms and histological subtype indicates two distinct aetiologies of gatric cardia cancer. [PDF]

open access: yes, 2008
<b>INTRODUCTION</b> Atrophic gastritis is a risk factor for non-cardia gastric cancer, and gastro-oesophageal reflux disease (GORD) for oesophageal adenocarcinoma.
Derakhshan, M.H.   +10 more
core   +1 more source

Epidemiology of Helicobacter pylori infection

open access: yesHelicobacter, 2018
This review provides the most recent data concerning the epidemiology of Helicobacter pylori infection. Overall, the trend of declining prevalence of H. pylori infection is continuing, with major evidence available from studies in Europe.
O. Sjomina, J. Pavlova, Y. Niv, M. Leja
semanticscholar   +1 more source

Disruption of salt bridge interactions in the inter‐domain cleft of the tubulin‐like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723

open access: yesCytoskeleton, EarlyView.
Abstract FtsZ forms a ring‐like assembly at the site of division in bacteria. It is the first protein involved in the formation of the divisome complex to split the cell into two halves, indicating its importance in bacterial cell division. FtsZ is an attractive target for developing new anti‐microbial drugs to overcome the challenges of antibiotic ...
Sakshi Mahesh Poddar   +3 more
wiley   +1 more source

Synonymous and Nonsynonymous Distances Help Untangle Convergent Evolution and Recombination [PDF]

open access: yesarXiv, 2014
When estimating a phylogeny from a multiple sequence alignment, researchers often assume the absence of recombination. However, if recombination is present, then tree estimation and all downstream analyses will be impacted, because different segments of the sequence alignment support different phylogenies.
arxiv  

Serum proteomic profiling of precancerous gastric lesions and early gastric cancer reveals signatures associated with systemic inflammatory response and metaplastic differentiation

open access: yesFrontiers in Molecular Biosciences
The noninvasive detection technique using serum for large-scale screening is useful for the early diagnosis of gastric cancer (GC). Herein, we employed liquid chromatography mass spectrometry to determine the serum proteome signatures and related ...
Yueqing Gong   +17 more
doaj   +1 more source

Metabolomic analysis of low and high biofilm-forming Helicobacter pylori strains

open access: yesScientific Reports, 2018
The biofilm-forming-capability of Helicobacter pylori has been suggested to be among factors influencing treatment outcome. However, H. pylori exhibit strain-to-strain differences in biofilm-forming-capability.
Eric Hong Jian Wong   +5 more
doaj   +1 more source

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