Results 11 to 20 of about 38,033 (184)
Helicobacter Infection and Gastric Adenoma [PDF]
Background: We aimed to provide insight into the actual frequencies of gastric adenoma types and their association with gastritis status and associated mucosal changes with a focus on Helicobacter infection and the operative link on gastritis assessment (OLGA)/operative link on gastric intestinal metaplasia assessment (OLGIM) staging. Methods: From the
Simone Bertz+8 more
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Helicobacter pyloriInfection [PDF]
Helicobacter pylori (H. pylori) colonizes the gastric mucosa of more than 50% of the human population. It is the major etiological agent of chronic gastritis, peptic ulcer, gastric mucosa-associated lymphoid tissue lymphoma, and gastric adenocarcinoma.
Ping-I Hsu+5 more
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Helicobacter Pylori Infection [PDF]
Infection with Helicobacter pylori (H. pylori) is a major pathogenic factor for gastroduodenal ulcer disease and gastric carcinoma, as well as for other types of gastric and extragastric disease. As a result of changing epidemiologic conditions (e.g., immigration), changing resistance patterns with therapeutic implications, and new knowledge relating ...
Wolfgang Fischbach, Peter Malfertheiner
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Immunomodulation of Helicobacter Infection [PDF]
Helicobacter pylorileads to a chronic infection in humans that is associated with gastric inflammation and a vigorous immune response. Despite the humoral and cellular responses that can be detected in both human and animal models of helicobacter infection, the immune response fails to eliminate the organism. Eradication failure may be due to the niche
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c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie+17 more
wiley +1 more source
Management of Helicobacter pylori infections [PDF]
Infection with Helicobacter pylori is associated with severe digestive diseases including chronic gastritis, peptic ulcer disease, and gastric cancer. Successful eradication of this common gastric pathogen in individual patients is known to prevent the occurrence of peptic ulcer disease and gastric cancer.With half of the world's population being ...
Amin Talebi Bezmin Abadi+1 more
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Gastric Infection by Helicobacter pylori [PDF]
Helicobacter pylori infection causes chronic active gastritis, ulcer disease, and gastric cancer. Current eradication regimens use a proton pump inhibitor (PPI) and two antibiotics. Triple therapy now has a success rate less than 80%, below the cutoff for efficacious eradication.
David R. Scott+4 more
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Pathogenicity of Helicobacter pylori infection [PDF]
Numerous Helicobacter pylori virulence factors, including various enzymes (urease, catalase, lipase, phospholipase and proteases), vacuolating cytotoxin (a product of expression of the vacA gene), and the immunogenic protein CagA, encoded by the cagA gene localised in the H.
Jarosław Jóźwiak+3 more
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Helicobacter pylori Infection and Anemia [PDF]
Dear Sir: In their comprehensive and rigorous study on the etiology of anemia in Cote d'Ivoire, Righetti and others1 reported high prevalence of anemia (45–75%), inflammation, and deficiencies of iron, riboflavin, and vitamin A. The factors that were significantly and positively linked to the prevalence of anemia differed by age group: (1) infection
Dani Cohen, Khitam Muhsen
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The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source