Imposition of Different Optimizing Object with Non-Linear Constraints on Flux Sampling and Elimination of Free Futile Pathways [PDF]
arXiv, 2007 Constraint-based modeling has been widely used on metabolic networks analysis, such as biosynthetic prediction and flux optimization. The linear constraints, like mass conservation constraint, reversibility constraint, biological capacity constraint, can be imposed on linear algorithms.
arxiv
The Helicobacter pylori AI-Clinician: Harnessing Artificial Intelligence to Personalize H. pylori Treatment Recommendations [PDF]
arXivHelicobacter pylori (H. pylori) is the most common carcinogenic pathogen worldwide. Infecting roughly 1 in 2 individuals globally, it is the leading cause of peptic ulcer disease, chronic gastritis, and gastric cancer. To investigate whether personalized treatments would be optimal for patients suffering from infection, we developed the H.
arxiv
Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials
Exploration, EarlyView.Intra‐tumoral microbiota, which is a potential component of the tumor microenvironment, has been emerging as a key participant and driving factor in cancer. This article reviews the latest progress in this field, including the microbial community within tumors and its pro‐cancer mechanisms, as well as the anti‐tumor strategies targeting intra‐tumoral ...
Yanan Niu +4 more
wiley +1 more source
Diagnosising Helicobacter pylori using AutoEncoders and Limited Annotations through Anomalous Staining Patterns in IHC Whole Slide Images [PDF]
arXivPurpose: This work addresses the detection of Helicobacter pylori (H. pylori) in histological images with immunohistochemical staining. This analysis is a time demanding task, currently done by an expert pathologist that visually inspects the samples. Given the effort required to localise the pathogen in images, a limited number of annotations might be
arxiv
Synthetic Biology‐Based Engineering Cells for Drug Delivery
Exploration, EarlyView.Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi +4 more
wiley +1 more source
Offdiagonal complexity: A computationally quick network complexity measure. Application to protein networks and cell division [PDF]
Mathematical Modeling of Biological Systems II. Ed. A.Deutsch et
al., Birkhaeuser Boston 291-299 (2007), 2007 Many complex biological, social, and economical networks show topologies drastically differing from random graphs. But, what is a complex network, i.e.\ how can one quantify the complexity of a graph? Here the Offdiagonal Complexity (OdC), a new, and computationally cheap, measure of complexity is defined, based on the node-node link cross-distribution,
arxiv
Berries: Health Effects via Modulation of the Gut Microbiota
Food Frontiers, EarlyView.ABSTRACT Berries are widely regarded as beneficial foods, rich in polyphenols, flavonoids, and other bioactive compounds that could positively influence human health. Although the gut microbiota plays a crucial role in metabolism and physiology of humans, the interaction between berries and human gut microbiota activity remains unclear.
Manjin Xu +11 more
wiley +1 more source
Helicobacter pyloriInfection and the Risk of Gastric Carcinoma [PDF]
, 1991 Julie Parsonnet +6 more
openalex +1 more source
Helicobacter pylori infection: the reduced need for ulcer surgery [PDF]
, 1999 The success of the eradication treatment for Helicobacter pylori in managing ulcer disease has further refined the indications for ulcer surgery. More patients are spared unnecessary surgery and its untoward sequelae.
Chu, KM
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