Results 131 to 140 of about 156,187 (258)

Association of Interleukin‐17F Polymorphisms (rs763780, rs9382084, rs2397084, and rs12203582) With Gastric Cancer Susceptibility According to Helicobacter pylori Infection Status

International Journal of Immunogenetics, EarlyView.
ABSTRACT Single nucleotide polymorphisms (SNPs) in the interleukin‐17F (IL‐17F) gene may modulate inflammatory responses, with distinct effects on inflammation and tumour progression. Helicobacter pylori infection, a Group 1 carcinogen, is strongly associated with gastric cancer (GC) development.
Mikaela Nagahara, Bruno Mari Fredi, Fabricio Abdalla Brandt, Alanis dos Santos Fonseca, Milena Milani Coelho, Danielli Girolli, Elizabeth Suchi Chen, Monica Santiago Barbosa, Spencer Luiz Marques Payao, Lucas Trevizani Rasmussen   +9 more
wiley   +1 more source

Downregulation of the Tumor Suppressor P53 Gene associated with the Progression of Clinical Staging and the Incidence of Distant Metastasis in Indonesian Colorectal Cancer

The Korean Journal of Gastroenterology
Background/Aims: A genome-wide study identified tumor suppressor P53 (TP53), BRAF, KRAS, COL-3A1, and SOCS-2 as key drivers of tumorigenesis in human colorectal cancers (CRC). We investigated the association between these molecules’ expression levels and
Yudith Annisa Ayu Rezkitha, Amal Arifi Hidayat, Irine Normalina, Maria Inge Lusida, Takashi Matsumoto, Yoshio Yamaoka, Muhammad Miftahussurur   +6 more
doaj   +1 more source

Management of chronic urticaria: Current status and future prospect

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chronic urticaria is driven by mast cell activation through autoimmune, inflammatory, and neuroimmune pathways. A structured approach combining diagnosis, patient‐reported outcomes, stepwise therapy, treatment optimization, monitoring and emerging targeted agents may improve disease control and enable more personalized management.
Andaç Salman, Mona Al‐Ahmad, Maryam Al‐Nesf, Chia‐Yu Chu, Luis Felipe Ensina, Ana M. Gimenez‐Arnau, Margarida Gonçalo, Clive Grattan, Michihiro Hide, Pavel Kolkhir, Martin Metz, Iman Nasr, Romi Saini, Simon Francis Thomsen, Torsten Zuberbier, Emek Kocaturk   +15 more
wiley   +1 more source

Association of Vitamin B6 and Homocysteine–ACTH Coupling With Depressive and Anxiety Symptoms in Burning Mouth Syndrome: An Exploratory Case–Control Study

Journal of Oral Rehabilitation, EarlyView.
In this exploratory case–control study, plasma PLP (vitamin B6), homocysteine and ACTH concentrations did not differ between patients with burning mouth syndrome (BMS) and controls, and none discriminated patients individually. Within patients, however, psychological distress mapped onto a homocysteine–ACTH relationship from which PLP appeared ...
Ashley Lebel, Charlotte Guillouet, André Porporatti, Yves Boucher   +3 more
wiley   +1 more source

Detection of Ring Structure and Its Flexibility in Periplasmic Region of FliL, Bacterial Flagellar Stator‐Associate Protein, in Marine Vibrio

Molecular Microbiology, EarlyView.
FliL, a single‐pass transmembrane flagellar protein with a large periplasmic domain, associates with the basal body and supports motor function under high‐load conditions (e.g., viscous environments). The periplasmic domain of deletion mutant FliL forms a flexible ring structure, likely reflecting the capacity of the full‐length protein to adaptively ...
Tatsuro Nishikino, Norihiro Takekawa, Raymond Burton‐Smith, Yuki Tajimi, Kazuyoshi Murata, Takayuki Uchihashi, Seiji Kojima, Katsumi Imada, Michio Homma   +8 more
wiley   +1 more source

Serum Level of Metalloproteinase in Patients Infected with Helicobacter Pylori in Ardabil [PDF]

Background & Objectives: Matrix Metalloproteinases (MMPs), a member of photolytic enzyme family, degrade the extra cellular matrix. MMPs have very important roles in physiological and pathological processes.
اتحاد, غلامحسین, امانی, مجتبی, پهلوان, یاسمین, پرستار, ندا   +3 more
core  

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

Current <i>Helicobacter pylori</i> Diagnostics: Established Methods, Resistance Testing, and Emerging Approaches. [PDF]

JGH Open
ABSTRACT Aims Accurate diagnosis of Helicobacter pylori infection is required to detect active infection, confirm eradication, assess gastric pathology when indicated, and obtain antimicrobial resistance information that may guide treatment. This review evaluates the clinical roles, limitations, and implementation maturity of established, molecular ...
Tang T, Paz EA, Yu K, Lee KH, Tay CY, Wang J, Marshall BJ, Hu L, Fu W, Yang Z.   +9 more
europepmc   +2 more sources

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Prospective screening of dyspeptic patients by Helicobacter pylori serology: a safe policy? The Italian Helicobacter pylori Study Group.

, 1997
BACKGROUND AND STUDY AIMS: Endoscopic screening of all dyspeptic patients is not cost-effective, nor is it feasible in many health-care delivery systems.
STANGHELLINI VINCENZO, CORINALDESI ROBERTO, The Italian Helicobacter pylori Study Group, PALLI DOMENICO, VAIRA DINO, MENEGATTI MARCELLO, MIGLIOLI MARIO, NERI, Matteo   +7 more
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