Results 81 to 90 of about 276,829 (341)

Gut microbiota and its therapeutic implications in tumor microenvironment interactions

Frontiers in Microbiology
The development of cancer is not just the growth and proliferation of a single transformed cell, but its tumor microenvironment (TME) also coevolves with it, which is primarily involved in tumor initiation, development, metastasis, and therapeutic ...
Pengya Feng, Pengya Feng, Pengya Feng, Xia Xue, Xia Xue, Ihtisham Bukhari, Ihtisham Bukhari, Chunjing Qiu, Chunjing Qiu, Yingying Li, Yingying Li, Pengyuan Zheng, Pengyuan Zheng, Yang Mi, Yang Mi   +14 more
doaj   +1 more source

Increased prevalence of precancerous changes in relatives of gastric cancer patients: critical role of H. pylori [PDF]

, 2000
Background & Aims:Helicobacter pylori is believed to predispose to gastric cancer by inducing gastric atrophy and hypochlorhydria. First-degree relatives of patients with gastric cancer have an increased risk of developing gastric cancer.
El–Nujumi, Adil, El–Omar, Emad M., Fullarton, Grant, Gillen, Derek, McColl, Kenneth E.L., Murray, Lilian S., Oien, Karin, Williams, Craig, Wirz, Angela   +8 more
core   +1 more source

Mucoadhesive Polyvinyl Alcohol Film Containing Fridericia chica Extract for Mucositis Treatment: Pharmacological Evaluation and Active Compounds Release

Chemistry &Biodiversity, EarlyView.
ABSTRACT Oral mucositis is a frequent and painful complication of cancer therapy with limited effective options. This study evaluated a mucoadhesive polyvinyl alcohol (PVA) film containing 2.5% Fridericia chica extract as a novel strategy. The formulation was characterized for antioxidant activity, phenolic and flavonoid content, and reactive species ...
Ilza Maria de Oliveira Sousa, Ailane Souza de Freitas, Fabrício de Faveri Favero, Lucia Elaine O. Braga, Mariana Cecchetto Figueiredo, Diana Pinto, Maria Beatriz P. P. Oliveira, Simone Nataly Busato de Feiria, Nubia de Cássia Almeida Queiroz, Ana Lucia T. G. Ruiz, José Francisco Hofling, João Ernesto de Carvalho, Mary Ann Foglio   +12 more
wiley   +1 more source

Interleukin-1 polymorphisms associated with increased risk of gastric cancer [PDF]

, 2000
Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer disease. The reasons for this variation are not clear, but the gastric physiological response is influenced by the severity and ...
A Cox, B Ruiz, CA Dinarello, Charles S. Rabkin, Chiu-Chin Yuan, Correa, P., CR Yu, D Basso, DM Parkin, E El-Omar, E El-Omar, EJ Kuipers, EM El-Omar, Emad M. El-Omar, F Pociot, George Lanyon, HC Jung, Howard A. Young, HW Chow, IL Beales, Jay H. Bream, Jesus Herrera, JL Wallace, Jolanta Lissowska, Joseph F. Fraumeni, Kenneth E. L. McColl, LA Noach, LE Hansson, M Carrington, Mary Carrington, Maureen Martin, MJ Blaser, MM Wolfe, NA Tountas, Nathaniel Rothman, P Sipponen, RM Royall, RW Stockbruegger, S Santtila, T Andus, VA Danis, Wong-Ho Chow, Y Yamaoka   +42 more
core   +2 more sources

Nonsteroidal Anti‐Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik, Ainhoa Gomez‐Lumbreras, Guilherme Del Fiol, Kensaku Kawamoto, Katy E. Trinkley, Thomas Reese, Aubrey Jones, Daniel C. Malone   +7 more
wiley   +1 more source

A novel sulfonamide derivative suppresses gastrointestinal cancer progression by targeting Axin2 and β-catenin

Scientific Reports
Gastrointestinal cancer is a major global health risk with rising incidence and limited effective therapeutic options. Despite advancements in diagnostics and therapies, the aggressive nature of these malignancies make novel therapeutic strategies ...
Xiaojie Li, Huijuan Wen, Le Chang, Xia Xue, Huayuan Xi, Ruoyu Hu, Mengke Rong, Pengyuan Zheng, Simeng Liu   +8 more
doaj   +1 more source

HELICOBACTER PYLORI INFECTION IN CHILDREN

Majalah Kedokteran Andalas, 2011
AbstrakFaktor risiko infeksi Helicobacter pylori adalah tinggal di negara berkembang, kondisi sosial ekonomi yang rendah, jumlah anggota keluarga yang banyak, etnik dan genetik.
Yusri Dianne Jurnalis, Yorva Sayoet, Sari Dewi   +2 more
doaj   +1 more source

Risk factors in gastric cancer [PDF]

, 2010
STATE OF THE ART: Gastric cancer (GC) is still a major health problem worldwide due to its frequency, poor prognosis and limited treatment options. At present prevention is likely to be the most effective means of reducing the incidence and mortality ...
COMPARE, DEBORA, NARDONE, GERARDO ANTONIO PIO, ROCCO, ALBA   +2 more
core  

The biological functions of IL-17 in different clinical expressions of Helicobacter pylori-infection [PDF]

, 2015
Helicobacter pylori (H. pylori) infection is regarded as the major cause of various gastric diseases (gastritis, peptic ulcers and gastric cancer) and induces the production of several cytokines.
Azadegan-Dehkordi, Fatemeh., Bagheri, Nader., Rafieian-Kopaei, Mahmoud., Rahimian, Ghorbanali., Razavi, Alireza., shirzad, Hedayatollah.   +5 more
core   +1 more source

Intestinal Barrier Glycosylation for Gut Physiology and Pathology

Barrier Immunity, EarlyView.
ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley   +1 more source