Avoid Internal Loops in Steady State Flux Space Sampling [PDF]
As a widely used method in metabolic network studies, Monte-Carlo sampling in the steady state flux space is known for its flexibility and convenience of carrying out different purposes, simply by alternating constraints or objective functions, or appending post processes.
arxiv
Survey of general practitioners' knowledge about Helicobacter pylori infection [PDF]
BACKGROUND: Helicobacter pylori, occurring throughout the world and causing gastroduodenal diseases, is one of the most common chronic bacterial agents in humans.
Canbaz, Sevgi+3 more
core +3 more sources
Measuring and estimating interaction between exposures on dichotomous outcome of a population [PDF]
In observational studies for the interaction between exposures on dichotomous outcome of a population, one usually uses one parameter of a regression model to describe the interaction, leading to one measure of the interaction. In this article, we use the conditional risk of outcome given exposures and covariates to describe the interaction and obtain ...
arxiv
Risk factors in gastric cancer [PDF]
STATE OF THE ART: Gastric cancer (GC) is still a major health problem worldwide due to its frequency, poor prognosis and limited treatment options. At present prevention is likely to be the most effective means of reducing the incidence and mortality ...
COMPARE, DEBORA+2 more
core
Membrane-bound β-catenin degradation is enhanced by ETS2-mediated Siah1 induction in Helicobacter pylori-infected gastric cancer cells. [PDF]
β-catenin has two different cellular functions: intercellular adhesion and transcriptional activity. The E3 ubiquitin ligase Siah1 causes ubiquitin-mediated degradation of the cytosolic β-catenin and therefore, impairs nuclear translocation and oncogenic
Bhattacharyya, A+7 more
core +1 more source
Identification of Essential Proteins Using Induced Stars in Protein-Protein Interaction Networks [PDF]
In this work, we propose a novel centrality metric, referred to as star centrality, which incorporates information from the closed neighborhood of a node, rather than solely from the node itself, when calculating its topological importance. More specifically, we focus on degree centrality and show that in the complex protein-protein interaction ...
arxiv
Impact of creatinine clearance on helicobacter pylori eradication rate in patients with peptic ulcer disease [PDF]
Introduction. Gastrointestinal complaints are common in patients with kidney failure. The aim of this study was to investigate the effect of creatinine clearance on Helicobacter pylori (HP) eradication rate in patients with peptic ulcer disease ...
Alimadadi, M.+6 more
core
Helicobacter suis affects the health and function of porcine gastric parietal cells [PDF]
The stomach of pigs at slaughter age is often colonized by Helicobacter (H.) suis, which is also the most prevalent gastric non-H. pylori Helicobacter (NHPH) species in humans. It is associated with chronic gastritis, gastric ulceration and other gastric
Ducatelle, Richard+5 more
core +4 more sources
ObjectiveColorectal cancer (CRC) is the third most prevalent cancer worldwide and is associated with high morbidity and mortality rates. Colorectal carcinogenesis occurs via the conventional adenoma-to-carcinoma and serrated pathways.
Qiao Meng+10 more
doaj +1 more source
Multi-omic Network Regression: Methodology, Tool and Case Study [PDF]
The analysis of biological networks is characterized by the definition of precise linear constraints used to cumulatively reduce the solution space of the computed states of a multi-omic (for instance metabolic, transcriptomic and proteomic) model.
arxiv