Results 101 to 110 of about 133,418 (255)

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source

Risk factors in gastric cancer [PDF]

, 2010
STATE OF THE ART: Gastric cancer (GC) is still a major health problem worldwide due to its frequency, poor prognosis and limited treatment options. At present prevention is likely to be the most effective means of reducing the incidence and mortality ...
COMPARE, DEBORA, NARDONE, GERARDO ANTONIO PIO, ROCCO, ALBA   +2 more
core  

Longitudinal Changes in the Serum Pepsinogen I/II Ratio With Progression of Gastric Atrophy

Journal of Clinical Laboratory Analysis, EarlyView.
Serum pepsinogen (PG) I/II ratio decreased with progression of gastric mucosal atrophy and showed consistent intra‐individual changes over time. In a large cohort with repeated endoscopic evaluations, longitudinal declines in the PG I/II ratio paralleled worsening atrophic stages.
Soie Chung, Jung Kim, Ji Hyun Song, Jooyoung Lee, Sun Young Yang, Eun Young Song   +5 more
wiley   +1 more source

The effect of microRNA-375 overexpression, an inhibitor of Helicobacter pylori-induced carcinogenesis, on lncRNA SOX2OT [PDF]

, 2016
Background: Helicobacter pylori is a major human pathogenic bacterium in gastric mucosa. Although the association between gastric cancer and H. pylori has been well-established, the molecular mechanisms underlying H.
Aleyasin, S.A., Mowla, S.J., Shafiee, M., Vasei, M., Yazdanparast, S.A.   +4 more
core   +1 more source

TDP-43-driven alternative splicing of UQCRC2 modulates mitochondrial bioenergetics

Biology Direct
TAR DNA-binding protein 43 (TDP-43) is a nuclear RNA-binding protein. It has emerged as a key regulator of RNA processing, such as alternative splicing events, which are essential for cellular homeostasis.
Xia Xue, Jingwen Hou, Zhiqi Zhang, Zeting Yang, Le Chang, Zengguang Yang, Simeng Liu, Huang Huang, Lu Mei, Yang Mi, Pengyuan Zheng, Xiangdong Sun   +11 more
doaj   +1 more source

Role of inflammation-related genes as prognostic biomarkers and mechanistic implications in idiopathic pulmonary fibrosis

Frontiers in Genetics
IntroductionIdiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive lung disorder characterized by excessive fibrosis and structural remodeling of lung tissue. The role of inflammation in developing and progressing IPF is increasingly recognized as
Bing Bai, Bing Bai, Bing Bai, Wenfei Zhao, Fazhan Li, Yang Mi, Pengyuan Zheng   +6 more
doaj   +1 more source

High prevalence of ultra‐short celiac disease in children with low anti‐tissue transglutaminase immunoglobulin A levels: The risk of misdiagnosis without bulb biopsy

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite recent advances in diagnostics, celiac disease (CD) diagnosis remains challenging. Ultra‐short celiac disease (USCD) has been proposed as a distinct phenotype characterized by villous atrophy confined to the duodenal bulb, positive celiac serology, and clinical features consistent with CD.
Antonio Pizzol, Eleonora Saraceno, Anna Opramolla, Laura Giugliano, Cristina Chiadò, Tilde Manetta, Gabriella Canavese, Enrico Falco, Michele Pinon, Pier Luigi Calvo   +9 more
wiley   +1 more source

Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth. [PDF]

, 2015
Lymphoid tissue inducer (LTi) cells are activated by accessory cell IL-23, and promote lymphoid tissue genesis and antibacterial peptide production by the mucosal epithelium.
Banerjee, A, Basappa, N, Blanchard, TG, Czinn, SJ, Ding, H, Drakes, ML, Fricke, WF, Kobayashi, KS, Piazuelo, MB, Shiu, J   +9 more
core   +2 more sources

Peptic ulcer disease: Insights and risk factors

JPGN Reports, EarlyView.
Abstract Objectives Peptic ulcer disease (PUD), affects adults and children, with Helicobacter pylori (H. pylori) infection being the most frequent cause. Diagnosis requires an upper gastrointestinal endoscopy (UGE) and invasive tests. However, besides H. pylori, risk factors for PUD in children remain unclear.
Haidar Houmani, Islam Saidi, Meline M'rini, Julie Nguyen, Assaad Salame, Patrick Bontems, Kallirroi Kotilea   +6 more
wiley   +1 more source

Interleukin-1 polymorphisms associated with increased risk of gastric cancer [PDF]

, 2000
Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer disease. The reasons for this variation are not clear, but the gastric physiological response is influenced by the severity and ...
A Cox, B Ruiz, CA Dinarello, Charles S. Rabkin, Chiu-Chin Yuan, Correa, P., CR Yu, D Basso, DM Parkin, E El-Omar, E El-Omar, EJ Kuipers, EM El-Omar, Emad M. El-Omar, F Pociot, George Lanyon, HC Jung, Howard A. Young, HW Chow, IL Beales, Jay H. Bream, Jesus Herrera, JL Wallace, Jolanta Lissowska, Joseph F. Fraumeni, Kenneth E. L. McColl, LA Noach, LE Hansson, M Carrington, Mary Carrington, Maureen Martin, MJ Blaser, MM Wolfe, NA Tountas, Nathaniel Rothman, P Sipponen, RM Royall, RW Stockbruegger, S Santtila, T Andus, VA Danis, Wong-Ho Chow, Y Yamaoka   +42 more
core   +2 more sources