Results 101 to 110 of about 69,057 (254)

Metabolomic and lipidomic signatures of Helicobacter pylori infection: Unveiling biochemical pathways associated with neurodegeneration

iMetaOmics, EarlyView.
Our study employed an integrated lipidomics and metabolomics approach to elucidate Helicobacter pylori‐driven metabolic perturbations along the gut–brain axis. H. pylori infection was established in gastric epithelial (AGS) cells, and the resulting conditioned media (secretome) was collected and exposed to neuronal (IMR‐32) cells.
Meenakshi Kandpal, Tarun Prakash Verma, Siddharth Singh, Hamendra Parmar, Hem Chandra Jha   +4 more
wiley   +1 more source

Formulation and evaluation of floating mucoadhesive alginate beads for targetingHelicobacter pylori [PDF]

, 2015
Objectives: There are various obstacles in the eradication of Helicobacter.pylori (H. pylori) infections, including low antibiotic levels and poor accessibility of the drug at the site of the infection.
Adebisi, Adebisi, Adeola O. Adebisi, Ahuja, Akiyama, Bai, Bajpai, Barbara R. Conway, Batchelor, Bazzoli, Boddupalli, Cammarota, Castro, Chun, Desai, Dunn, Dupuy, Erah, Erah, Ernst, Gal, Georgopoulos, Gåserød, Higuchi, Hixson, Iijima, Ikeda, Ishak, Kawahara, Khanvilkar, Kohri, Korsmeyer, Lee, Lehmann, Malfertheiner, Miyazaki, Moore, Murata, Murray, Najib, Nakagawa, Nayak, Norris, Park, Pasparakis, Pereira, Peter R. Laity, Peterson, Rajinikanth, Romero, Rothenbacher, Singh, Smrdel, Stops, Suerbaum, Suzuki, Umamaheshwari, Varum, Whitehead, Østberg   +59 more
core   +1 more source

Socioeconomic Status Modifies the Risk of Gastric Cancer Through Metabolomic Signature: Evidence From a Prospective Cohort Study

iNew Medicine, EarlyView.
ABSTRACT The role of metabolites in the association between socioeconomic status (SES) and gastric cancer remains unclear. This study seeks to elucidate the role of metabolomics in the association between SES and gastric cancer, as well as to explore potential interactions between metabolic signatures and polygenic risk score (PRS) in the context of ...
Shiyin Meng, Shangxin Zhang, Jing Wang, Zhuoyi Wu, Wenjie Xuan, Jiawei Zhang, Qihong Zhao, Anla Hu, Jing Ni   +8 more
wiley   +1 more source

Presence and significance of Helicobacter spp. in the gastric mucosa of Portuguese dogs [PDF]

, 2015
Background: Non-Helicobacter pylori Helicobacters (NHPH) are also able to cause disease in humans. Dogs are a natural reservoir for many of these species. Close and intense human contact with animals has been identified as a risk factor and therefore, an
Alves, Odete, Amorim, Irina, Gärtner, Fátima, Haesebrouck, Freddy, Reis, Celso, Saraiva, Ana Laura, Smet, Annemieke, Taulescu, Marian, Teixeira, Silvia   +8 more
core   +3 more sources

Analyzing The effect of metformin on eradication of H.Pylori infection in the patients 25 -75 years old referring Loghman Hakim hospital

Caspian Journal of Internal Medicine, 2022
Background: Various ways of treating H.pylori infection are reported, such as triple-therapy and quadruple therapy for two weeks. Some side effects have been seen during these treatments, besides Helicobacter pylori becoming resistant to these ...
Shahriar Nikpour, Mohammad Salehi, Sina Homaee, Farnaz Saberian, Saeid Kalbasi   +4 more
doaj  

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source

The biological functions of IL-17 in different clinical expressions of Helicobacter pylori-infection [PDF]

, 2015
Helicobacter pylori (H. pylori) infection is regarded as the major cause of various gastric diseases (gastritis, peptic ulcers and gastric cancer) and induces the production of several cytokines.
Azadegan-Dehkordi, Fatemeh., Bagheri, Nader., Rafieian-Kopaei, Mahmoud., Rahimian, Ghorbanali., Razavi, Alireza., shirzad, Hedayatollah.   +5 more
core   +1 more source

Longitudinal Changes in the Serum Pepsinogen I/II Ratio With Progression of Gastric Atrophy

Journal of Clinical Laboratory Analysis, EarlyView.
Serum pepsinogen (PG) I/II ratio decreased with progression of gastric mucosal atrophy and showed consistent intra‐individual changes over time. In a large cohort with repeated endoscopic evaluations, longitudinal declines in the PG I/II ratio paralleled worsening atrophic stages.
Soie Chung, Jung Kim, Ji Hyun Song, Jooyoung Lee, Sun Young Yang, Eun Young Song   +5 more
wiley   +1 more source

Study of association between helicobacter pylori infection and microalbuminuria in type-2 diabetic patients [PDF]

, 2015
BACKGROUND/AIMS: As default, Helicobacter pylori infection may cause systemic inflammation and vascular endothelial damage. Therefore, it can be assumed that the glomerular damage as a result may lead to an increase in urinary albumin excretion. In this
Moghni, M., Reiisi, S., Shahi, H.
core  

Helicobacter pylori infection appears essential for stomach carcinogenesis: Observations in Semarang, Indonesia [PDF]

, 2005
The gastric cancer incidence in Semarang, Indonesia, is exceedingly low: only approximately 1/100th of the level in Japan. To elucidate the reason, we carried out an ecological study recruiting 69 male and 102 female participants from the general ...
Ghadimi, Reza, Hosono, Akihiro, Miranti, Ika P., Moore, Malcolm A., Samsuria, Witjitra D., Sarjadi, Sarjadi, Soeripto, Soeripto, Suzuki, Sadao, Tokudome, Shinkan, Triningsih, F. X. Ediati, Triono, Teguh, Wijaya, Indra   +11 more
core   +1 more source