Results 201 to 210 of about 130,724 (273)

Computational Validation of Multi‐Epitope mRNA Vaccine Targeting Streptococcus anginosus Surface Protein (TMPC) as an Effective Alternative Treatment to Reduce Gastric Cancer

open access: yesMicrobiologyOpen, Volume 15, Issue 1, February 2026.
Design process for messenger RNA vaccines. Candidate proteins are initially screened using immunoinformatics, after which selected epitopes are assembled into a multi‐epitope vaccine. The vaccine construct was evaluated through molecular docking, molecular dynamics simulations, and in silico immune simulations, followed by population coverage analysis ...
Fei Zhu   +7 more
wiley   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian   +8 more
wiley   +1 more source

Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu   +4 more
wiley   +1 more source

The Impact of Helicobacter pylori Infection on Retinal Nerve Fiber Layer and Macula. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Miao H   +15 more
europepmc   +1 more source

Gut Microbial Variations Associated With Proton Pump Inhibitor Use in the Boston Puerto Rican Health Study

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT Proton pump inhibitors (PPI), used to treat gastrointestinal disorders, are associated with alterations in the gut microbiome. However, this is understudied in Puerto Ricans who have unique lifestyle characteristics. Puerto Ricans, including participants of the Boston‐Puerto Rican Health Study (BPRHS), report high PPI use.
Deepika Dinesh   +10 more
wiley   +1 more source

Seroprevalence of Helicobacter pylori Infection Among Asymptomatic Patients Served by a Safety-Net Healthcare System. [PDF]

open access: yesClin Gastroenterol Hepatol
Thrift AP   +31 more
europepmc   +1 more source

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