Results 201 to 210 of about 69,057 (254)

Hericium erinaceus Extracts Exert Gastroprotective Effects Through Modulation of the Gut Microbiota and Metabolites

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
WEHE attenuates gastric injury by modulating the “gut microbiota–metabolites” axis. ABSTRACT Hericium erinaceus (H. erinaceus) is a traditional edible and medicinal fungus with a long history of use in gastrointestinal protection. Although its therapeutic potential in gastric health has been widely acknowledged, the underlying mechanisms by which it ...
Ruixin Bei, Lifan Yu, Zhonghua Lu, Tingxuan Zong, Yanfang Sun   +4 more
wiley   +1 more source

LL‐37: Biological Mechanisms and Emerging Therapeutic Applications in Intestinal Disease

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Human cathelicidin peptide LL‐37 is encoded by the CAMP gene and plays a key role in innate immunity. It maintains intestinal homeostasis through antibacterial, immunomodulation, and tissue repair functions. This paper reviews the multiple functions of LL‐37 in the intestinal‐immune axis and its contribution to intestinal immune homeostasis. A
Qichao Liu, Peng Xu, Cheng Zhang
wiley   +1 more source

Outer Membrane Vesicles Mediate the Secretion and Nuclear Trafficking of a Bacterial Nucleomodulin

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
(A) We propose that Helicobacter pylori secretes a nucleomodulin, Tumour Necrosis Factor‐α‐inducing protein (Tipα), predominantly via extracellular vesicles (EVs), also known as outer membrane vesicles, rather than as free protein. (B) EVs carrying Tipα enter eukaryotic cells by endocytosis and independently of surface‐expressed nucleolin, then traffic
Jack K. Emery, Variya Nemidkanam, Nina Colon, Kate R. J. Friesen, Lena H. M. Le, Angus R. Cramond, Maxine Yap, Mônica S. Barbosa, Georgie Wray‐McCann, David J. McGee, Natalia Castaño‐Rodríguez, Dongmei Tong, Caroline Skene, Laurent Terradot, Richard L. Ferrero   +14 more
wiley   +1 more source

Gut Microbiota and Extraintestinal Cancers: Mechanistic Insights and Microbiome‐Targeted Interventions

JGH Open, Volume 10, Issue 5, May 2026.
ABSTRACT The gut microbiota is a dynamic community of bacteria, viruses, fungi, and archaea that plays a pivotal role in regulating host immunity, metabolism, and systemic homeostasis. Dysbiosis, characterized by an imbalance in the microbial composition, is being increasingly recognized as a contributor not only to gastrointestinal cancers but also to
Rishi Chowdhary, Manjeet Kumar Goyal, Kirti Arora, Tanisha Sehgal, Prachi Dawer, F. N. U. Anirudh, Jeffrey Berinstein, Shrinivas Bishu, Laurie Matt‐Amaral   +8 more
wiley   +1 more source

Multicenter experience using tofacitinib for treatment of refractory pediatric inflammatory bowel diseases in the United States

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 5, Page 1218-1225, May 2026.
Abstract Objectives Tofacitinib is a selective Janus kinase (JAK‐1) inhibitor approved for the treatment of ulcerative colitis (UC) in adults. Data is limited in the pediatric population. The aim of this study was to evaluate the efficacy of tofacitinib in pediatric inflammatory bowel disease (IBD).
Denise D. Young, Jennifer E. Murphy, Mallory Chavannes, Jennifer L. Dotson, Jeanne Tung, Erica Chang, Brad Pasternak, Erin Crawford, Nancy McGreal, Jonathan Moses, Sandra C. Kim   +10 more
wiley   +1 more source

Factors related to loss to follow‐up and low compliance in Helicobacter pylori‐infected children: The EuroPedHp Registry

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 5, Page 1178-1192, May 2026.
Factors related to loss to follow‐up and low compliance in Helicobacter pylori‐infected children. Abstract Objectives Monitoring for Helicobacter pylori (H. pylori)‐eradication is important, since symptom improvement does not indicate treatment success. Using EuroPedHp Registry data, we investigated characteristics of children missing monitoring visits
Thu Giang Le Thi, Kallirroi Kotilea, José Cabral, Michal Kori, Maria Luz Cilleruelo, Marta Tavares, Josefa Barrio, Vaidotas Urbonas, Matjaž Homan, Zrinjka Misak, Nicolas Kalach, Pedro Urruzuno, Martina Klemenak, Andreas Krahl, Andrea Chiaro, Josef Sykora, Meltem Korkut Ugras, Jan de Laffolie, Erasmo Miele, Alexandra Papadopoulou, Sibylle Koletzko, for the Helicobacter pylori & Other Gastritis Special Interest Group of ESPGHAN, Thu Giang Le Thi, Kallirroi Kotilea, José Cabral, Michal Kori, Maria Luz Cilleruelo, Marta Tavares, Josefa Barrio, Vaidotas Urbonas, Matjaž Homan, Zrinjka Misak, Nicolas Kalach, Pedro Urruzuno, Martina Klemenak, Andreas Krahl, Andrea Chiaro, Josef Sykora, Meltem Korkut Ugras, Jan de Laffolie, Erasmo Miele, Alexandra Papadopoulou, Sibylle Koletzko   +42 more
wiley   +1 more source

Menetrier's: A pediatric chronic state of disease with a possible heritable form

JPGN Reports, Volume 7, Issue 2, Page 259-261, May 2026.
Abstract Menetrier's disease (MD) is a rare, typically transient, hypertrophic gastropathy with under 1000 adult cases and 50 pediatric cases known worldwide. Pediatric cases most often present with an infectious etiology. We present a case of a teenage male expressing a chronic state of disease without infectious origin.
MariaElena Terzis, Anna Furr, Julia Fritz   +2 more
wiley   +1 more source

Delayed diagnosis of 3β‐HSD7 deficiency in adolescence: Two case reports and review of the literature

JPGN Reports, Volume 7, Issue 2, Page 236-241, May 2026.
Abstract Congenital bile acid synthesis defects (BASD), the most common of which is 3β‐hydroxy‐Δ5‐C27‐steroid dehydrogenase oxidoreductase (3β‐HSD7) deficiency, are a rare cause of fat‐soluble vitamin malabsorption. We describe a 14‐year‐old girl who presented at 14 months with a left distal femur fracture and failure to thrive.
Samantha Pendleton, Mojdeh Mostafavi, Jamie Mathew, Kayla Ganzburg, Barry Hirsch, Nadia Ovchinsky, Wael Sayej   +6 more
wiley   +1 more source

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Helicobacter pylori infection

Nature Reviews Disease Primers, 2023
Helicobacter pylori infection causes chronic gastritis, which can progress to severe gastroduodenal pathologies, including peptic ulcer, gastric cancer and gastric mucosa-associated lymphoid tissue lymphoma. H. pylori is usually transmitted in childhood and persists for life if untreated. The infection affects around half of the population in the world
Peter Malfertheiner, M. Constanza Camargo, Emad El-Omar, Jyh-Ming Liou, Richard Peek, Christian Schulz, Stella I. Smith, Sebastian Suerbaum   +7 more
openaire   +2 more sources

Helicobacter pylori Infection

Gastroenterology Clinics of North America, 2021
Helicobacter pylori infection remains one of the most prevalent infections worldwide, causing significant morbidity and mortality from gastric malignancies and peptic ulcers. This article provides a summary of the microbiology and pathogenesis of this bacterium, emphasizing the complex and protean effects of H pylori on gastric epithelial cells ...
Jaehoon, Cho, Akriti, Prashar, Nicola L, Jones, Steven F, Moss   +3 more
openaire   +2 more sources