Results 71 to 80 of about 370,970 (310)

Expanding Our Understanding of Help-Seeking Behavior: Implications for Older Adults at Elevated Risk of Suicide

open access: yes
Suicide is a serious public health concern, especially among older adults who present with historically high rates of suicide (CDC, 2023). Despite these disproportionate rates of suicide, little research has examined help-seeking behavior among older ...
Shaikh, Afroze N
core   +1 more source

Patient delays in seeking help at the onset of rheumatoid arthritis: the problem, its causes and potential solutions

open access: yes, 2013
Rheumatoid arthritis (RA) is a chronic inflammatory disease for which early treatment is vital to limit long term joint damage. However, people often delay in seeking medical help at the onset of RA symptoms.
Stack, Rebecca   +8 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Help-seeking behavior among community-dwelling adults with chronic pain

open access: yesCanadian Journal of Pain, 2019
Background Some individuals with chronic pain do not seek care. This decision may be due to characteristics of the individual, pain, and/or their health professional(s).
Elizabeth G. Mann   +3 more
doaj   +1 more source

Help seeking behavior

open access: yes, 1999
The purpose of this study was to identify factors that may affect counseling psychology doctoral students' tendencies to seek professional psychological help for their personal problems.
Farber, Nancy Karen
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Disclosure and help seeking behavior of women exposed to physical spousal violence in Dhaka slums

open access: yesBMC Public Health, 2016
Background Despite high prevalence of intimate partner violence (IPV) and its adverse social and health consequences, the rate of help seeking for IPV is generally low.
Kausar Parvin   +2 more
doaj   +1 more source

Help seeking of adolescents when faced with a psychological problem

open access: yes, 2011
This thesis explored the help seeking of adolescents. In particular it focused on who adolescents seek help from for particular problems, the relationship between the options they selected, gender, previous help seeking and psychological distress, their ...
de Bruin, Marizanne
core  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

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