Results 61 to 70 of about 1,881,560 (314)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Adolescents, beliefs and help-seeking [PDF]

open access: yes, 2019
Background. Mental health services remains the least preferred choice for help-seeking in adolescents. To date, there is scarce literature regarding adolescents’ beliefs about mental health services and how their beliefs have impacted on the decision to ...
Pascua-Leones, K.
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A proposed novel digital condylar position adjustment technique to help restore a normal disc-condyle relationship

open access: yesHeliyon
Objectives: To demonstrate a novel digital technique that enables real-time visualisation of occlusal transfer and adjustment of condyle position, to (1) improve the repeatability of occlusal transfer and the accuracy of condyle position adjustment and ...
Yanji Gong   +6 more
doaj   +1 more source

Help Me TripAdvisor! Examining the Relationship between TripAdvisor e-WOM Attributes, Trusts towards Online Reviews and Travellers Behavioural Intentions

open access: yesJournal of Information and Organizational Sciences, 2020
This paper aims to examine the impact of TripAdvisor reviews on behavioural intentions, basing on travellers' trust towards the e-WOM reviews. Four factors are proposed for building travellers’ trust and behavioural intentions: information quality ...
Nur Zarifah Dhabitah Mahat   +1 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Help seeking of adolescents when faced with a psychological problem

open access: yes, 2011
This thesis explored the help seeking of adolescents. In particular it focused on who adolescents seek help from for particular problems, the relationship between the options they selected, gender, previous help seeking and psychological distress, their ...
de Bruin, Marizanne
core  

Temporary help agencies and occupational mobility [PDF]

open access: yes, 2003
This paper focuses upon the effect of Temporary Help Agencies (THAs) on occupational mobility through a comparison of the job-to-job upgrading chances of THA and non-THA workers.
Fernando Muñoz-bullón   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Premarital education and later relationship help-seeking. [PDF]

open access: yes, 2018
Despite evidence that empirically supported couple therapies improve marital relationships, relatively few couples seek help when they need it. Low-income couples are particularly unlikely to engage in relationship interventions despite being at greater ...
Williamson, Hannah C   +9 more
core   +1 more source

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