Results 41 to 50 of about 440,093 (308)

Predictors of Professional Help-Seeking Intention Toward Depression Among Community-Dwelling Populations: A Structural Equation Modeling Analysis

open access: yesFrontiers in Psychiatry, 2022
BackgroundA low intention of professional help seeking hinders the effective treatment of depression. The factors are from the perspectives of the social, family, and individual; however, an understanding of how they interact to predict professional help-
Xin Yi Li   +12 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Usability testing of the Pathway app: engaging stakeholders to improve access to mental health support for students

open access: yesFrontiers in Digital Health
BackgroundMental health difficulties are highly prevalent among university students. Evidence shows that a majority of university students do not seek professional mental health support for their difficulties.
Olugbenga Oti, Sarah Foley, Ian Pitt
doaj   +1 more source

Teacher Help-Seeking Beliefs and Help-Seeking Networks [PDF]

open access: yes, 2015
Teachers work within a network of teachers at their school whose members can be an important source of advice and help, yet they must seek help from their colleagues in order to benefit from this network. This study employs social network analysis to examine how help-seeking patterns among teachers are related to teachers’ curricular domain, years of ...
Makara Fuller, Kara, Karabenick, Stuart
openaire  

Patterns and risk factors with help-seeking for common mental disorders in an urban Malaysian community [PDF]

open access: yes
Common mental disorders (CMD) is used to describe depressive and anxiety disorders. Community prevalence rates worldwide are estimated between 15%-30%. Mental health services however are mainly geared towards those with the more severe forms of mental
Ismail, Siti Irma Fadhilah
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Factors for Perceived Helpfulness of Support Sources Among Survivors of Intimate Partner Violence

open access: yesBehavioral Sciences
Intimate partner violence (IPV) has far-reaching health and social consequences, particularly for survivors experiencing polyvictimization—multiple forms of IPV such as physical, emotional, and sexual abuse. This study examined help-seeking behaviors and
Hyunkag Cho   +3 more
doaj   +1 more source

Adolescents, beliefs and help-seeking [PDF]

open access: yes, 2019
Background. Mental health services remains the least preferred choice for help-seeking in adolescents. To date, there is scarce literature regarding adolescents’ beliefs about mental health services and how their beliefs have impacted on the decision to ...
Pascua-Leones, K.
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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