Results 61 to 70 of about 440,093 (308)

Relationship between mental health literacy and professional psychological help-seeking attitudes in China: a chain mediation model

open access: yesBMC Psychiatry, 2023
Background Mental health literacy is considered an important factor in promoting professional psychological help-seeking attitudes. However, it is important to clarify the emotional and behavioral factors that underlie this association.
Jingyuan Yang   +4 more
doaj   +1 more source

The influence of masculinity on white and south Asian men's help seeking behaviour for chest pain [PDF]

open access: yes, 2006
Coronary heart disease is the leading cause of premature death for men in the UK. The mortality rate is almost twice as high for South Asian men living in the UK compared to the rest of the population. There is established evidence that prompt diagnosis
Galdas, Paul Michael
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Young people's beliefs about help-seeking for first episode psychosis [PDF]

open access: yes, 2012
The importance of early intervention for positive outcomes following a first episode of psychosis (FEP) is recognised, however, there are still delays in young people seeking help.
Glossop, H.
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The Process of Seeking Treatment for Mental Health Problems

open access: yes, 2007
A model of the process of seeking treatment for mental health problems is presented that explicates much previous research in this area. A process comprising seven steps is proposed (recognize that there is a problem, decide the problem is mental health ...
Saunders, Stephen   +3 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Asian cultural values and help-seeking: a cross-sectional study on compulsive sexual behavior

open access: yesFrontiers in Psychiatry
BackgroundSexuality is a complex construct influenced by various social and cultural factors, and while sexual behavior is generally considered adaptive for physical and mental well-being, it can become uncontrollable and harmful, leading to Compulsive ...
Hoang-Long Pham   +13 more
doaj   +1 more source

Attitudes towards mental illness and psychological help seeking in Syria: an exploratory study [PDF]

open access: yes, 2015
The overall aim of this thesis was to understand how mental health and seeking help for mental health problems were understood in Syria. The initial investigation began by examining whether or not Western mental health concepts and measures were ...
Al-kurdi, M.
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy