Results 61 to 70 of about 2,367,021 (309)

Male frequent attenders of general practice and their help seeking preferences [PDF]

, 2011
Background: Low rates of health service usage by men are commonly linked to masculine values and traditional male gender roles. However, not all men conform to these stereotypical notions of masculinity, with some men choosing to attend health services ...
Adshead F., Alan K. White, Anne-Marie Bagnall, Corney R.H., Courtenay W.H., Galdas P.M., George A., Green C.A., Harrison A., Heywood P., Jane South, Karl R. Witty, Macintyre S., Möller-Leimkühler A.M., Noone J.H., Randall M., Robertson S., Scaife B., Shalev V., Shapiro S., Smith J.A., Smith J.A., Smith J.A., Vedsted P., Wilkins D.   +24 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The role of social goal orientation and academic help-seeking behavior on mathematics achievement of primary students

Cogent Education
The purpose of this study was to examine the role of students' social goal orientation and academic help seeking behavior on their mathematics achievement. Data were collected from 930 Grade 8 primary school students in Ethiopia.
Fasika Teshale Wole, Reda Darge Negasi, Amare Sahile Abebe   +2 more
doaj   +1 more source

Help Seeking Behaviour of Adolescents at Kolar

Journal of Clinical and Biomedical Sciences, 2016
Background: Adolescents are full of energy, have significant drive and new ideas. They are a posi-tive force for the nation and are mostly responsible for its future productivity, provided they undergo over-all development in a healthy manner ...
Radha MS, Lavanya Subhashini, Immanuel Prabhu, Baby GK Banubi   +3 more
doaj   +1 more source

Cognitive and Social Help Giving in Online Teaching: An Exploratory Study [PDF]

, 2009
While literature suggests that college students may be less reluctant to seek help in online rather than traditional courses, little is known about how online instructors give help in ways that lead to increased student help seeking and academic success.
Lorentz, Rebecca A., Whipp, Joan
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Factors Contributing to College Men\u27s Help-seeking [PDF]

, 2012
This study sought to explore factors relating to college-men\u27s decision to pursue counseling at a college-based counseling center. In particular, the relationship between percentage of male-counselor\u27s to male college students utilization rates ...
Caperton, William
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Personality and help-seeking for psychological distress: a systematic review and meta-analysis

Frontiers in Psychiatry
IntroductionThe effective management of depression, anxiety, and other forms of psychological distress depends on individuals’ readiness to seek and accept help for their mental suffering. Understanding which personality traits relate to help-seeking can
Anna Szücs, Anna Szücs, Anna Szücs, Rachel Hui Xin Lam, Wymann Shao Wen Tang, Lifan Zhou, Monica Lazarus, Andrea B. Maier, Andrea B. Maier, Andrea B. Maier, Jose M. Valderas, Jose M. Valderas, Jose M. Valderas   +12 more
doaj   +1 more source