Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
About the difficult art of helping. Book reviev Refugees Among Us Aid in an Interdisciplinary Perspective edited by Ewa Kurantowicz [PDF]
The article is a discussion of a book dedicated to aid activities addressed to refugees from Ukraine after the start of hostilities. The reviewed book was based on projects which showed the socio-cultural dimension of helping.
Witold Jakubowski
doaj +1 more source
Helping, holding, hurting: recalling and reforming punishment [PDF]
The Criminal Justice and Licensing (Scotland) Bill currently before the Scottish Parliament represents one of the most significant planned reforms of punishment in Scotland for generations.
McNeill, Fergus
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
I’ll be there for you? The bystander intervention model and cyber aggression
The Bystander Intervention Model (BIM) has been validated for face-to-face emergencies and dictates that observers’ decision to intervene hinges on five sequential steps, while barriers block progress between steps.
Vasileia Karasavva, Amori Mikami
doaj +1 more source
Helping out by helping in : approaches to electronic submission of coursework [PDF]
In this paper, we seek to address a range of issues that affect the use and applicability of electronic coursework submission. Key among these issues is the need to characterise the available mechanisms for supporting such submission.
Weir, G.R.S.
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Level of physical Activity in Patients with Fatty Liver - A Cross Sectional study
Background: Liver with fatty appearance illness is a common disorder that is caused by addition of extra fats in the liver. Fats make up 5% to 10% of the weight of the liver, it becomes an issue and it is termed as steatosis.
Adnan Ahmed +5 more
doaj
Nonzero-Sum Time Perception Is Associated with Greater Willingness to Help
People are less likely to help others when they view time as a scarce resource. Does changing people’s perception of time influence their willingness to help?
Yu Niiya +3 more
doaj +1 more source
HEALTH: Helping Employees Alter Life Through Health [PDF]
To create a healthier and happier company environment and network as a whole. Our employees will become more focused and goal-oriented driven.
Rains, Alyssa, Strabala, Natalie
core +1 more source

