Results 111 to 120 of about 3,123,409 (310)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Consumer Engagement: Helping People Want What They Need [PDF]
, 2016 Developing or delivering a product, tool, or service that meets consumers' needs and leads to impactful behavior change is a significant challenge. Simply creating tools to foster financial security has not been enough to ensure that consumers will use ...
Kristen Bryant, Timothy Flacke
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tendency of physical Activity in Type 2 diabetic Patients of hazara division
Journal Riphah College of Rehabilitation SciencesA chronic disease, diabetes type II that had resistance towards insulin elevated level of glucose. The occurrence of T2DM in Pakistan raised and it is increased by obesity, dietary intake and sedentary lifestyle.
Adnan Ahmed +3 more
doaj
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Helping Kindergarteners Make Sense of Numbers to 100 [PDF]
, 2009 The authors share what was learned about kindergarteners\u27 abilities to make sense of numbers to 100 when one of the authors, Linda Jaslow, took over a kindergarten class from February through the end of the school year.
Jacobs, V. R., Jaslow, L. B.
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The efficacy of active spirituality in mitigating burnout and promoting wellness in the counseling profession [PDF]
, 2017 Burnout presents an enormous risk to the helping professionals, and by proxy, the people they intend to help. The relationship between spirituality, religion, and burnout in the counseling profession was examined through review of quantitative ...
Anton, Mark S., Farner, Katherine A.
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source