Results 41 to 50 of about 563,399 (342)

Listening to Users' Voice: Automatic Summarization of Helpful App Reviews [PDF]

open access: yesarXiv, 2022
App reviews are crowdsourcing knowledge of user experience with the apps, providing valuable information for app release planning, such as major bugs to fix and important features to add. There exist prior explorations on app review mining for release planning, however, most of the studies strongly rely on pre-defined classes or manually-annotated ...
arxiv  

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Turning Our Gaze to Prosocial Media Effects: What is and isn’t Known

open access: yesEmpirical Musicology Review, 2015
Clark and Giacomantonio (2015) raise several valuable research questions concerning the relationship between empathy and music genre preferences, and present interesting exploratory analyses concerning this issue.
Sara Prot, Douglas Gentile
doaj   +1 more source

Pro-social behavior in rats is modulated by social experience

open access: yeseLife, 2014
In mammals, helping is preferentially provided to members of one’s own group. Yet, it remains unclear how social experience shapes pro-social motivation.
Inbal Ben-Ami Bartal   +4 more
doaj   +1 more source

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

open access: yesFEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr   +4 more
wiley   +1 more source

Message Framing Effects on Individuals' Social Distancing and Helping Behavior During the COVID-19 Pandemic

open access: yesFrontiers in Psychology, 2021
This research responds to urgent calls to fill knowledge gaps on COVID-19 (new coronavirus) in communicating social distancing messages to the public in the most convincing ways. The authors explore the effectiveness of framing social distancing messages
Melis Ceylan, Ceren Hayran
doaj   +1 more source

Influence of committed volunteers on helping behavior in emergency evacuations [PDF]

open access: yesarXiv, 2021
We study how the presence of committed volunteers influences the collective helping behavior in emergency evacuation scenarios. In this study, committed volunteers do not change their decision to help injured persons, implying that other evacuees may adapt their helping behavior through strategic interactions.
arxiv  

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

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