Results 91 to 100 of about 1,366,098 (338)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Community workers frequently experience significant job stress during public health emergencies, which may adversely impact their prosocial behavior.
Dongxu Guo, Zhifeng Wang
doaj +1 more source
Patient Education and Consumer Activation in Chronic Disease [PDF]
Presents suggestions from experts on patient and provider education, health behavior change, and information technologies for strategies, tactics, and activities for helping the chronically ill become active participants in their health and health ...
core
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Kişilerin yaşadıklarıolayların nedenlerini nelere atfettikleri, kişisel kontrol odaklarıile ilgili olup, çalıştıklarıörgütte sergileyecekleri nezaket ve yardım etme davranışlarınıetkileyebilmektedir.
H. Nejat Basım, Harun Şeşen
doaj
Promoting Helping Behavior with Framing in Dictator games. [PDF]
A number of recent papers on double-blind dictator games have obtained significant generous behavior when information regarding the recipient or any other social context is provided.
Pablo Brañas-Garza
core
The Neurocognitive Process of Digital Radicalization: A Theoretical Model and Analytical Framework [PDF]
Recent studies suggest that empathy induced by narrative messages can effectively facilitate persuasion and reduce psychological reactance. Although limited, emerging research on the etiology of radical political behavior has begun to explore the role of
Benning, Stephen D. +2 more
core +2 more sources
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source

