Results 111 to 120 of about 1,366,098 (338)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Helping but Not Always Empathic: Helping Behavior, Dispositional Empathic Concern, and the Principle of Care [PDF]
, 2006 This research investigates the relative strength of dispositional empathic concern and a moral principle to care about others as correlates of helping behavior.
Bekkers, Rene, Wilhelm, Mark O.
core
Prosocial Virtual Reality, Empathy, and EEG Measures: A Pilot Study Aimed at Monitoring Emotional Processes in Intergroup Helping Behaviors [PDF]
, 2020 Francesca D’Errico +3 more
openalex +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
New simulations to qualify eutectic lithium-lead as breeder material [PDF]
, 2011 Pb17Li is today a reference breeder material in diverse fusion R&D programs worldwide. One of the main issues is the problem of liquid metals breeder blanket behavior.
Caro, Alfredo +4 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Judgment and Decision MakingThe identified victim effect is the phenomenon in which people tend to contribute more to identified than to unidentified victims. Kogut and Ritov (Journal of Behavioral Decision Making, 18(3), 157–167, 2005) found that the identified victim effect was ...
Rajarshi Majumder +3 more
doaj +1 more source
Interpersonal and Ideological Kindness: A Biocultural Approach [PDF]
, 2018 In accordance with Richard Dawkins’ materialist “selfish gene” theory of human behavior, altruism is a subject matter that is treated conservatively by biologists, whose understanding of the human version of altruism tends toward mutualistic and ...
Averitt-Hubbard, Sally
core +2 more sources
HELPING VULNERABLE POPULATIONS THROUGH PROGRAMS FOCUSED ON THE SOCIAL AND BEHAVIORAL DETERMINANTS OF HEALTH [PDF]
, 2018 G M Waterman, Nicholas Wilson
openalex +1 more source