Results 51 to 60 of about 103,741 (283)

Depression of excitatory synapses onto parvalbumin interneurons in the medial prefrontal cortex in susceptibility to stress [PDF]

, 2015
In response to extreme stress, individuals either show resilience or succumb to despair. The prefrontal cortex (PFC) is required for coping with stress, and PFC dysfunction has been implicated in stress-related mental disorders, including depression ...
Delevich, K., Li, B., Perova, Z.
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Mediating role of learned helplessness’ components in the association between health literacy/social support and self-management among maintenance haemodialysis patients in Changsha, China: a cross-sectional study

BMJ Open, 2023
Objectives To explore the multiple mediating roles of the learned helplessness’s core system in the relationship between health literacy/social support and self-management.Design Cross-sectional survey design.Setting Changsha, China.Participants 239 ...
Li Li, Lin Zhou, Yamin Li, Chunyan Xie, Cuifang Sun, Yini Zhang   +5 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The Effect of Vicarious Learned Helplessness on Critical Thinking [PDF]

, 2007
This study was to determine if critical thinking was affected by vicarious learned helplessness. Learned helplessness is a psychological condition in which one continues to be hurt or damaged physically or mentally.
Hennessey, Bridget
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Effectiveness of psychological empowerment training program based on individual psychology Adler's theory on female-headed household’s learned helplessness [PDF]

Faṣlnāmah-i Farhang Mushavirah va Ravān/Darmānī, 2017
Purpose: The objective of this study was to determine the effectiveness of psychological empowerment training program based on individual psychology Adler's theory on female-headed household’s learned helplessness.
Alireza karimivakil, Abdollah Shafiabadi, kiiumars farahbakhsh, jalil younesi   +3 more
doaj   +1 more source

Beberapa Bentuk Perilaku Underachievement Dari Perspektif Teori Self Re-gulated Learning [PDF]

, 2005
Underachievement is generally caused by factors related to students behaviors which do not support their learning. This article discusses some behaviors leading to underachievement, namely amotivation, learned helplessness, self handicapping, and ...
Sunawan, S. (Sunawan)
core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Responding to Sexual Discrimination: The effects of societal versus self-blame [PDF]

, 1994
While self-blame has been considered to be a useful coping tool for victims, its benefits within the context of group discrimination are equivocal. The present research hypothesized that women encouraged to engage in self-blame for sex discrimination ...
Foster, Mindi D, Matheson, Kimberley, Poole, Megan   +2 more
core   +3 more sources