Results 61 to 70 of about 11,664 (246)

Unravelling the interplay of grit, learned helplessness, and vocabulary proficiency in ELT students

open access: yesActa Psychologica
Positive psychology, which focuses on well-being and life satisfaction, has attracted significant attention from researchers in educational context, particularly in language learning and teaching.
Elham Azad, Mehmet Ali Yavuz
doaj   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

The Hoffman report, the Central Intelligence Agency, and the defense of the nation: A personal view

open access: yesHealth Psychology Open, 2018
I was asked by the Central Intelligence Agency in the spring of 2002 about how the research on learned helplessness could help captured Americans resist and evade torture and interrogation.
Martin Seligman
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

The Relationship between 8th Grade Students’ Opinions about Problem Solving, Beliefs about Mathematics, Learned Hopelessness and Academics Success

open access: yesGaziantep Üniversitesi Sosyal Bilimler Dergisi, 2017
Related literature emphasizes that affective factors are impactful on cognitive factors. For this reason, this study aims at revealing the relationship between problem solving,  which is one of metacognitive characteristics, beliefs about mathematics and
Gülay Agaç, Ercan MASAL
doaj   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

The Interrelation Between Culturally Learned Helplessness and Economic Underdevelopment

open access: yesUniversal Journal of History and Culture
This article offers insights into the interrelationship between culturally learned helplessness and economic underdevelopment. It is argued that the concept of learned helplessness offers noteworthy insights into the nature of economic underdevelopment ...
Ferhat Öztutuş, Yunus Eroğlu
doaj   +1 more source

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