Results 111 to 120 of about 43,528 (269)

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

Shear Bond Strength of MDP-Containing Adhesives with and without HEMA: An in Vitro Study

Erbil Dental Journal
Background and Objectives: The primary role of dental adhesives is to deliver a good bond between the filling material and the tooth. Universal adhesive (UA) systems brought a novel concept by adding active resin monomers that facilitate both ...
Ahmed S. Hasan, Shakhawan K. Kadir
doaj   +1 more source

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source

Rescue of the endogenous FVIII expression in hemophilia A mice using CRISPR-Cas9 mRNA LNPs

Molecular Therapy: Nucleic Acids
Gene editing provides a promising alternative approach that may achieve long-term FVIII expression for hemophilia A (HemA) treatment. In this study, we investigated in vivo correction of a mutant factor VIII (FVIII) gene in HemA mice.
Chun-Yu Chen, Xiaohe Cai, Barbara A. Konkle, Carol H. Miao   +3 more
doaj   +1 more source

Patch Test Reactions to Dental Materials: A Retrospective Single-Centre Study. [PDF]

Contact Dermatitis
In this retrospective single‐centre study of 439 adults referred for suspected delayed‐type hypersensitivity to dental materials, 50.1% had at least one positive patch test reaction, most often to metals. Nickel (23.0%) and palladium (16.6%) pre‐dominated, whilst methacrylate positivity was uncommon (6.2%) and not fully captured by HEMA alone.
Bizjak-Suran M, Marčun M, Košnik M, Dinevski D.   +3 more
europepmc   +2 more sources

Use of an Oral Health‐Related Quality of Life Instrument to Measure Unmet Dental Care Needs in Adults With Inherited Bleeding Disorders

Haemophilia, EarlyView.
ABSTRACT Introduction Preventive dental care is vital for individuals with bleeding disorders to reduce the need for potentially invasive procedures. Although dental care is a mandated function of U.S. federally supported hemophilia treatment centers (HTCs), access to dental care is widely variable.
Miguel A. Escobar, Megan M. Ullman, Joanna Larson, Michael M. Chan, Marisela Trujillo   +4 more
wiley   +1 more source

Direct Resin Composite and Lithium Disilicate Endocrowns in Severely Compromised Endodontically Treated Molars: A Two‐Year Randomized Controlled Trial

International Endodontic Journal, EarlyView.
ABSTRACT Aim This randomized controlled superiority trial aimed to compare the clinical performance (restoration survival, clinical quality, and patient satisfaction) of direct resin composite and lithium disilicate endocrown restorations in structurally compromised endodontically treated molars.
Maurits C. F. M. de Kuijper, Carline R. G. van den Breemer, Yvonne C. M. de Waal, Lieke Lanjouw, Mutlu Özcan, Marco S. Cune, Marco M. M. Gresnigt   +6 more
wiley   +1 more source

Feasibility, Safety, and Efficacy of Pulsed Field Ablation for Ventricular Arrhythmias: Insights From a Large Health System Registry in the United States

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Pulsed field ablation (PFA) is an emerging non‐thermal ablation modality with proven safety in atrial arrhythmia ablation. However, data on its performance for ventricular arrhythmias (VA) remain limited. Objective To evaluate the feasibility, safety, and efficacy of PFA for complex VA in a multicenter real‐world US registry ...
Narut Prasitlumkum, Juan F. Rodriguez‐Riascos, Hema Vemulapalli, Aakash Somappa, Camilo A. Estrada‐Vargas, Olubadewa A. Fatunde, Carlos A. Rojas, Poojan Prajapati, Keerthika Vijayakumar, Suraj Kapa, Duy Nguyen, Samuel Asirvatham, Malini Madhavan, Christopher McLeod, Hicham Z. El Masry, Abhishek J. Deshmukh, Danesh K. Kella, Ammar M. Killu, Siva K. Mulpuru, Mayank Sardana, Luis R. Scott, Alan M. Sugrue, Komandoor Srivathsan   +22 more
wiley   +1 more source

6‐Month Clinical Evaluation of Reduced Dentin Etching Time Using Universal Adhesives in Noncarious Cervical Lesions: A Double‐Blind Randomized Clinical Trial

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objectives To evaluate the effect of reduced dentin etching time on the clinical performance of two universal adhesive systems in noncarious cervical lesions (NCCLs). Methods A total of 144 NCCLs restorations were randomly placed in 36 participants according to four experimental groups: SUP5 (Scotchbond Universal Plus adhesive [pH ≈2.5–2.7 ...
Mario Felipe Gutiérrez, Natalia Amo‐Nicolás, Alondra Beniscelli‐Vásquez, Romina Aliaga‐Gálvez, Alessandro D. Loguercio   +4 more
wiley   +1 more source

Influence of Universal Adhesives With or Without Silane Compared to One‐Step and Two‐Step Silane Agents on Bond Strength to Lithium Disilicate

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To evaluate the microshear bond strength (μSBS) to lithium disilicate achieved with universal adhesives (with and without silane) compared with one‐step and two‐step silanes, immediately (IM) and after thermocycling (TC). Chemical interaction (CI) was also assessed.
Camilo Pulido, Michel Wendlinger, Gabriel David Cochinski, Camila Farias Monteles, Alessandro Dourado Loguercio   +4 more
wiley   +1 more source