Results 81 to 90 of about 2,137 (194)
, 2018 The development of hydrogels for protein delivery requires protein-hydrogel interactions that cause minimal disruption of the protein's biological activity. Biological activity can be influenced by factors such as orientation and conformation. Hydrogels must promote the adsorption of biomolecules onto the surface and the diffusion of biomolecules into ...
Sen-Britain, Shohini +3 more
openaire +2 more sources
Contact Dermatitis, EarlyView.This study identified multiple areas for improvement in the regulatory risk assessment process. Conclusions based on predictive sensitization data should be made with caution, read‐across data from known sensitizers should be utilized, and epidemiological and patient threshold data should be prioritized in decision‐making.
Mathias Krogh Pedersen +7 more
wiley +1 more source
Patch Test Reactions to Dental Materials: A Retrospective Single‐Centre Study
Contact Dermatitis, EarlyView.In this retrospective single‐centre study of 439 adults referred for suspected delayed‐type hypersensitivity to dental materials, 50.1% had at least one positive patch test reaction, most often to metals. Nickel (23.0%) and palladium (16.6%) pre‐dominated, whilst methacrylate positivity was uncommon (6.2%) and not fully captured by HEMA alone.
Mojca Bizjak‐Suran +3 more
wiley +1 more source
Contact Dermatitis, EarlyView.We report three cases of allergic contact dermatitis (ACD) caused by acrylic resins used in creative hobbies, rather than by epoxy resins, despite these products being incorrectly labelled as “epoxy UV” resins. ABSTRACT Background Several cases of contact allergy to epoxy resins used in creative hobbies have been reported in recent years but not to ...
Nadia Raison‐Peyron +4 more
wiley +1 more source
Optimization of HEMA composition in polymer gel dosimeters for cost-effective radiation measurement
Proceedings of the Nigerian Society of Physical SciencesPolymer gel dosimeters (PGDs) are potential tools for radiation measurement in radiotherapy treatment planning systems (TPSs) and nuclear energy monitoring.
Muhammad Alhassan +2 more
doaj +1 more source
Contact Dermatitis, EarlyView.A case series of eight patients with allergic otitis externa from contact allergy to hearing aid ear moulds is presented. All were patch test positive to tetrahydrofurfuryl methacrylate and three to isobornyl acrylate. It is postulated that these are likely relevant allergens present in such devices. ABSTRACT Background Allergic contact dermatitis from
Norbertus A. Ipenburg +2 more
wiley +1 more source
Cell Proliferation, EarlyView.Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li +6 more
wiley +1 more source
Developmental Medicine &Child Neurology, EarlyView.Abstract Aim To examine the effectiveness of BRIGHT Coaching, a virtual coaching intervention, to increase parental empowerment in caregivers awaiting developmental services for their child. Method BRIGHT Coaching, a 12‐topic program, was developed by experts and parent‐partners to address caregivers' knowledge needs.
Annette Majnemer +17 more
wiley +1 more source
Haemophilia, EarlyView.ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner +59 more
wiley +1 more source
Gene Editing for Haemophilia—The Next Frontier
Haemophilia, EarlyView.ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti +3 more
wiley +1 more source