Results 181 to 190 of about 6,736 (217)

Rapid titration of viral hemagglutinins and hemagglutination inhibition antibodies with the aid of a fragiligraph

Experientia, 1965
Une methode est decrite pour la mesure des hemagglutinines virales et des anticorps inhibiteurs des hemagglutinines au moyen d'un systeme photoelectrique et enregistreur automatique — le fragiligraphe. Une suspension des erythrocytes et du virus est introduite dans la microcuvette du fragiligraphe.
A, Kohn, D, Danon
openaire   +2 more sources

Viral hemagglutinin augments peptide‐specific cytotoxic T cell responses

European Journal of Immunology, 1993
AbstractIn attempt to increase the induction of peptide‐specific cytolytic T cells (CTL) we investigated the effect of the Newcastle disease virus (NDV) hemagglutinin‐neuraminidase (HN) gene product on the activation of peptide‐specific CTL. Spleen cells of CH3 mice immunized against the influenza nucleoprotein peptide 50–63 (NP 50–63) were ...
C, Ertel, N S, Millar, P T, Emmerson, V, Schirrmacher, P, von Hoegen   +4 more
openaire   +2 more sources

The carboxyterminus of the hemagglutinin-neuraminidase of Newcastle disease virus is exposed at the surface of the viral envelope

Virus Research, 1984
The amino-terminal and the carboxy-terminal amino acids of the hemagglutinin-neuraminidase glycoprotein of the Ulster strain of Newcastle disease virus have been analyzed before and after proteolytic activation of the precursor HNo (Mr approximately 82K).
W, Schuy, W, Garten, D, Linder, H D, Klenk   +3 more
openaire   +2 more sources

Characterization of influenza virus neuraminidase with hemagglutinin activity and its comparison with that of viral neuraminidase

Biochimica et Biophysica Acta (BBA) - General Subjects, 1986
The neuraminidase associated with the bifunctional protein, hemagglutinin-neuraminidase, of influenza virus has been characterized. The enzyme has a pH optimum of 4.5, does not require Ca2+ and is inactivated (98%) by incubation at 50 degrees C. The enzyme has a Km of 2.00 X 10(-3) M and 0.06 X 10(-3) M with the substrates 2-(3-methoxyphenyl)-N ...
D J, Arora, L F, Gabriel
openaire   +2 more sources

A Simple Viral Neuraminidase-Based Detection for High-Throughput Screening of Viral Hemagglutinin–Host Receptor Specificity

2014
The correlation between precise interactions of influenza A virus hemagglutinins with host cell surface glycans having terminal sialic acids and host range specificity has provoked the development of a high-throughput viral-receptor specificity assay.
Nongluk, Sriwilaijaroen, Yasuo, Suzuki
openaire   +2 more sources

Release of viral hemagglutinin and nucleocapsid components after disruption of Sindbis virus with ether

Canadian Journal of Microbiology, 1971
Purified Sindbis virus is split into two components upon treatment with ether. These are (a) a hemagglutinin which sediments at 55 S and is non-infectious. This fraction was shown to be devoid of phospholipid and to contain the envelope structural protein of the virion; (b) a fraction sedimenting at 135 S, which is devoid of RNA, but contains viral ...
B, Arif, P, Faulkner
openaire   +2 more sources

Identification of immunodominant CD8 epitope in the stalk domain of influenza B viral hemagglutinin

Biochemical and Biophysical Research Communications, 2018
Human infections by type B influenza virus constitute about 25% of all influenza cases. The viral hemagglutinin is comprised of two subunits, HA1 and HA2. While HA1 is constantly evolving in an unpredictable fashion, the HA2 subunit is highly conserved, making it a potential candidate for a universal vaccine. However, immunodominant epitopes in the HA2
Abenaya, Muralidharan, Caroline, Gravel, Amparo, Duran, Louise, Larocque, Changgui, Li, Adrian, Zetner, Gary, Van Domselaar, Lisheng, Wang, Xuguang, Li   +8 more
openaire   +2 more sources

Simultaneous quantification of the viral antigens hemagglutinin and neuraminidase in influenza vaccines by LC–MSE

Vaccine, 2012
Current methods for quality control of inactivated influenza vaccines prior to regulatory approval include determining the hemagglutinin (HA) content by single radial immunodiffusion (SRID), verifying neuraminidase (NA) enzymatic activity, and demonstrating that the levels of the contaminant protein ovalbumin are below a set threshold of 1 μg/dose. The
Marybeth C, Creskey, Changgui, Li, Junzhi, Wang, Michel, Girard, Barry, Lorbetskie, Caroline, Gravel, Aaron, Farnsworth, Xuguang, Li, Daryl G S, Smith, Terry D, Cyr   +9 more
openaire   +2 more sources

The uncleaved viral hemagglutinin HA0 increases influenza A virus resistance to thermal pasteurization

Virology
Two biological types of influenza virus are known and distinguished by the structure of the surface glycoprotein, hemagglutinin (HA). The noninfectious virions contain the uncleaved HA0 (80 kDa), whereas the infectious type have a cleaved form of two subunits, HA1 (55 kDa) and HA2 (25 kDa).
O.P. Zhirnov, A.I. Chernyshova
openaire   +2 more sources

THE ROLE OF THE REOVIRUS HEMAGGLUTININ IN VIRAL VIRULENCE*

Annals of the New York Academy of Sciences, 1980
B N, Fields, H L, Weiner, D T, Drayna, A H, Sharpe   +3 more
openaire   +2 more sources