Results 41 to 50 of about 2,253 (164)

Familial Cerebral Cavernous Malformations: Pathophysiology, Genetics, Biomarkers, and Treatment Perspectives

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
Cerebral cavernous malformations (CCMs) are vascular lesions in the brain caused by inherited genetic mutations in the CCM1/2/3 genes that disrupt normal blood vessel function. This work demonstrates that these mutations lead to endothelial dysfunction, inflammation, and iron accumulation, which can be detected by magnetic resonance imaging (MRI) and ...
Fabrícia Lima Fontes‐Dantas, Gustavo da Fontoura Galvão, Alexandre Martins Cunha, Pedro de Sena Murteira Pinheiro, Verônica Morandi, Jorge Marcondes de Souza   +5 more
wiley   +1 more source

FamiIial vascuIar malformations Report of 25 members of one family [PDF]

, 1984
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65932/1/j.1399-0004.1984.tb04371.x ...
Barre, Bicknell, Clark, Foo, Foo, Goldberg, Graf, Hayman, Higginbottom, Ide, Kaplan, Kidd, King, Kufs, Laing, Lee, McCormick, McIntosh Nicol, Nova, Riley, Russel, Sarrat, Shelley, Snead, Stoll, Tay, Tonnie, Tonning, Trell, Zaremba   +29 more
core   +1 more source

A case of urgent neurosurgical treatment of intracerebral hemorrhage due to rupture of a cavernous hemangioma because of the progressive clinical deterioration

Українська Інтервенційна Нейрорадіологія та Хірургія, 2023
Cavernous hemangiomas (CH) are benign vascular lesions of the central nervous system, which are thin-walled vascular sinusoids without smooth muscle with hemosiderin deposits.
M.S. Gudym, I.M. Bortnik, M.B. Vyval
doaj  

Comparative Clinical Outcomes of Different Orbitotomy Approaches in the Surgical Management of Orbital Tumors

Journal of Ophthalmology, Volume 2026, Issue 1, 2026.
Background Optimal surgical management of orbital tumors requires precise selection of the surgical approach to achieve complete tumor removal while preserving visual function and maintaining cosmetic outcomes. Objective This study aimed to evaluate and compare the clinical outcomes of different orbitotomy approaches—including lateral, inferior ...
Karen Sevterteryan, Kamo Shaboyan, Gagik Hakobyan, Yasar Sakarya   +3 more
wiley   +1 more source

Microsurgical Outcomes in 1000 Patients With Cerebellopontine Angle Tumors: A Comprehensive Cohort Analysis

Otolaryngology–Head and Neck Surgery, Volume 173, Issue 5, Page 1236-1244, November 2025.
Abstract Objective To summarize the outcomes of 1000 consecutive microsurgical resection of cerebellopontine angle tumors. Study Design Retrospective cohort study. Setting Single tertiary care institution. Methods We analyzed 1000 patients who underwent microsurgical resection of cerebellopontine angle tumors between November 2017 and August 2024 ...
Joshua Lee, Michael G. Brandel, Benjamin T. Ostrander, Philipp Verpukhovskiy, Alena Pauley, Abhishek Bhatt, Alexandra Vacaru, Douglas M. Bennion, Marc S. Schwartz, Rick Friedman   +9 more
wiley   +1 more source

Clinical study on CyberKnife for treating giant cavernous hemangioma in cavernous sinus region

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
Objective To investigate the efficacy and safety of CyberKnife for giant cavernous hemangioma in cavernous sinus. Methods The data of 7 cases of giant cavernous hemangioma in cavernous sinus region confirmed by imaging examination and treated with ...
Lu SUN, Long-sheng PAN, Wei-jun WANG, Jin-yuan WANG, Zhi-zhong ZHANG, Zhong-jian JU, Zhi-pei LING, Bao-lin QU, Xin-guang YU   +8 more
doaj  

Propranolol therapy for cerebral cavernous malformations [PDF]

, 2022
Funding Information: The present study was funded by IPOLFG EPE and by iNOVA4Health (UID/Multi/04462/2019) a program finan‑ cially supported by Fundação para a Ciência e Tecnologia (FCT)/Ministério da Educação e Ciência, through national funds.
Conde, Sílvia V., Domingues, Germana, Gouveia-Fernandes, Sofia, Hipolito, Ana, Lopes-Coelho, Filipa, Martins, Filipa, Melo, Bernardete F., Nunes, Sofia, Pereira, Sofia A., Sacramento, Joana F., Salgado, Duarte, Serpa, Jacinta, Vinhais, Sofia   +12 more
core   +1 more source

Clinical study of intercellular adhesion molecule⁃1 expression in endothelial⁃derived exosome in children with intracranial cavernous hemangioma with epilepsy

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To investigate the expression and mechanism of exosomal intercellular adhesion molecule ⁃ 1 (ICAM ⁃ 1) in patients with intracranial cavernous hemangioma (CCM) associated epilepsy.
Bin LI, Hui ZHOU, Ai⁃qin JIN
doaj  

International Veterinary Epilepsy Task Force recommendations for systematic sampling and processing of brains from epileptic dogs and cats [PDF]

, 2015
Traditionally, histological investigations of the epileptic brain are required to identify epileptogenic brain lesions, to evaluate the impact of seizure activity, to search for mechanisms of drug-resistance and to look for comorbidities.
A Jeans, A Katelaris, A Klang, A Pakozdy, A Pakozdy, A Pitkanen, A Woznicka, Akos Pakozdy, AM Wahle, Andrea Fischer, Andrea Tipold, Clare Rusbridge, DM Kowalska, Edward E. Patterson, ES Park, Eva Wagner, F Reinoso-Suárez, Francisco Fernández-Flores, G Isoardo, H Potschka, H Urbach, Heidrun Potschka, HO Lüders, Holger A. Volk, I Blumcke, I Toyoda, IK Hwang, J O’Muircheartaigh, Jacques Penderis, JE Cavazos, JH Margerison, JN Kornegay, JY Cheong, K Baiker, K Kobow, Karen Muñana, Kaspar Matiasek, L Wang, LP Hudson, Luisa De Risio, M Fischer, M Manford, M Oehmichen, M Sasaki, M Singer, M Thom, M Thom, M Wolf, Marco Rosati, Martí Pumarola i Batlle, ME Milne, Mette Berendt, Michael Podell, MP Witter, N Shihab, PS Buckmaster, R Adamec, R Crooks, RE Adamec, RE Adamec, RM Packer, RN Auer, Robyn G. Farquhar, S Lomoio, S Schriefl, Sam Long, Simon Platt, Sofie F. M. Bhatti, SY Bando, T Kuwabara, TS Jokinen, U Seneviratne, VA Gil, Veronika M. Stein, Y Masuo, Z Ahmed   +75 more
core   +7 more sources

Leiomyoma Causing Disease in a Wild Adriatic Sturgeon (Acipenser naccarii, Bonaparte, 1836)

Journal of Fish Diseases, Volume 48, Issue 10, October 2025.
ABSTRACT The Adriatic sturgeon, Acipenser naccarii, is an endemic species to the Adriatic Sea basin classified as critically endangered according to the IUCN Red List. Limited information is available regarding the health status and diseases affecting this species, particularly in the wild.
A. Marsella, T. Pretto, C. Samassa, P. Tedesco, F. Pascoli, L. Congiu, A. Gustinelli, F. Borghesan, A. Toffan   +8 more
wiley   +1 more source