Results 91 to 100 of about 149 (149)
ABSTRACT Background Postpartum haemorrhage (PPH) is the leading cause of maternal mortality. Uterotonics are the mainstay of PPH prevention. Objectives To compare the efficacy of misoprostol and oxytocin for the prevention of PPH and to evaluate the trustworthiness of these randomised controlled trials (RCTs).
Madeline Flanagan+12 more
wiley +1 more source
Effects of sodium fluoride on serum concentrations of selected psychotropic drugs
Abstract Caution is imperative when interpreting drug concentrations in blood, plasma, or serum, given the potential variance in the distribution of a compound across these fluids. Preservatives, such as sodium fluoride, prove beneficial in preventing drug degradation in collected blood samples. This study aimed to examine the impact of sodium fluoride
Jennifer Liut+6 more
wiley +1 more source
Abstract Introduction This study aims to investigate patient factors affecting the rate of plasma volume target attained in hypertriglyceridemic pancreatitis (HTG‐AP) patients undergoing double filtration plasmapheresis (DFPP). Methods A retrospective analysis of 82 HTG‐AP‐interpreted patients from January 2019 to April 2024 compared target plasma ...
Hui Zhang, Chenqiang Zhu, Yunlong Wu
wiley +1 more source
The urban environment may exert different selective pressures on sexually selected traits than more pristine environments. Our study shows that sexual coloration is more saturated (bluer) in male lizards from urban environments than in male non‐urban lizards. The average parasite load is lower in urban lizards than in non‐urban lizards.
Juan C. GONZÁLEZ‐MORALES+4 more
wiley +1 more source
We analyzed clinical data from 2412 Golden Retrievers to examine age‐related changes and their association with mortality. A biological aging clock using blood markers achieved R = 0.78 but did not improve mortality prediction. A full biomarker model predicted lifetime (C‐index = 0.763) and 1‐year mortality (AUC = 0.817) more effectively.
Kevin Perez+3 more
wiley +1 more source
Differential Organ Ageing Is Associated With Age‐Related Macular Degeneration
Using the UK Biobank, this study trained neural networks to estimate the biological age of individuals according to markers of organ function. Computing the difference between the estimated organ age and chronological age yielded an estimate for accelerated or slowed ageing.
Anastasios Papadam+2 more
wiley +1 more source
Longevity Humans Have Youthful Erythrocyte Function and Metabolic Signatures
Longevity humans have “a youthful erythrocyte function and metabolism” with a youth‐like oxygen release and anti‐oxidative capability to combat tissue hypoxia and improve healthspan. ABSTRACT Longevity individuals have lower susceptibility to chronic hypoxia, inflammation, oxidative stress, and aging‐related diseases.
Fang Yu+17 more
wiley +1 more source
Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments
The association of the aging scores with the clinical covariates suggests increased inflammation, strong predisposition to iron deficiency anemia, decline in muscle mass, and renal and hepatic functions with accelerated aging. ABSTRACT The study of biomarkers in biofluids and tissues expanded our understanding of the biological processes that drive ...
R. Moaddel+17 more
wiley +1 more source
Nicotinamide riboside improved arterial stiffness (cardio–ankle vascular index), reduced skin ulcer area, and showed a trend toward mitigating heel pad thinning in patients with Werner syndrome, with no serious adverse events. Metabolomic analysis revealed a significant decrease in creatinine, suggesting a potential suppression of renal functional ...
Mayumi Shoji+15 more
wiley +1 more source