Results 91 to 100 of about 149 (149)

Misoprostol Versus Oxytocin for the Prevention of Postpartum Haemorrhage: A Systematic Review and Meta‐Analysis Including Individual Participant Data

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Postpartum haemorrhage (PPH) is the leading cause of maternal mortality. Uterotonics are the mainstay of PPH prevention. Objectives To compare the efficacy of misoprostol and oxytocin for the prevention of PPH and to evaluate the trustworthiness of these randomised controlled trials (RCTs).
Madeline Flanagan   +12 more
wiley   +1 more source

Effects of sodium fluoride on serum concentrations of selected psychotropic drugs

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Caution is imperative when interpreting drug concentrations in blood, plasma, or serum, given the potential variance in the distribution of a compound across these fluids. Preservatives, such as sodium fluoride, prove beneficial in preventing drug degradation in collected blood samples. This study aimed to examine the impact of sodium fluoride
Jennifer Liut   +6 more
wiley   +1 more source

Influence of patient factors on target plasma volume treated attainment rate during double filtration plasmapheresis in patients with hypertriglyceridemic acute pancreatitis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
Abstract Introduction This study aims to investigate patient factors affecting the rate of plasma volume target attained in hypertriglyceridemic pancreatitis (HTG‐AP) patients undergoing double filtration plasmapheresis (DFPP). Methods A retrospective analysis of 82 HTG‐AP‐interpreted patients from January 2019 to April 2024 compared target plasma ...
Hui Zhang, Chenqiang Zhu, Yunlong Wu
wiley   +1 more source

Bluer in the city: urban male lizards exhibit more intense sexual coloration and lower parasite loads than non‐urban males

open access: yesIntegrative Zoology, EarlyView.
The urban environment may exert different selective pressures on sexually selected traits than more pristine environments. Our study shows that sexual coloration is more saturated (bluer) in male lizards from urban environments than in male non‐urban lizards. The average parasite load is lower in urban lizards than in non‐urban lizards.
Juan C. GONZÁLEZ‐MORALES   +4 more
wiley   +1 more source

Lifetime age‐related changes in clinical laboratory results, aging clocks and mortality predictors in 2412 Golden Retrievers

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
We analyzed clinical data from 2412 Golden Retrievers to examine age‐related changes and their association with mortality. A biological aging clock using blood markers achieved R = 0.78 but did not improve mortality prediction. A full biomarker model predicted lifetime (C‐index = 0.763) and 1‐year mortality (AUC = 0.817) more effectively.
Kevin Perez   +3 more
wiley   +1 more source

Differential Organ Ageing Is Associated With Age‐Related Macular Degeneration

open access: yesAging Cell, Volume 24, Issue 5, May 2025.
Using the UK Biobank, this study trained neural networks to estimate the biological age of individuals according to markers of organ function. Computing the difference between the estimated organ age and chronological age yielded an estimate for accelerated or slowed ageing.
Anastasios Papadam   +2 more
wiley   +1 more source

Longevity Humans Have Youthful Erythrocyte Function and Metabolic Signatures

open access: yesAging Cell, Volume 24, Issue 5, May 2025.
Longevity humans have “a youthful erythrocyte function and metabolism” with a youth‐like oxygen release and anti‐oxidative capability to combat tissue hypoxia and improve healthspan. ABSTRACT Longevity individuals have lower susceptibility to chronic hypoxia, inflammation, oxidative stress, and aging‐related diseases.
Fang Yu   +17 more
wiley   +1 more source

Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments

open access: yesAging Cell, EarlyView.
The association of the aging scores with the clinical covariates suggests increased inflammation, strong predisposition to iron deficiency anemia, decline in muscle mass, and renal and hepatic functions with accelerated aging. ABSTRACT The study of biomarkers in biofluids and tissues expanded our understanding of the biological processes that drive ...
R. Moaddel   +17 more
wiley   +1 more source

Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial

open access: yesAging Cell, EarlyView.
Nicotinamide riboside improved arterial stiffness (cardio–ankle vascular index), reduced skin ulcer area, and showed a trend toward mitigating heel pad thinning in patients with Werner syndrome, with no serious adverse events. Metabolomic analysis revealed a significant decrease in creatinine, suggesting a potential suppression of renal functional ...
Mayumi Shoji   +15 more
wiley   +1 more source

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