Results 11 to 20 of about 25,879 (167)

Symptomatic Vulvar Primary Cutaneous Amyloidosis Associated With Low-Risk HPV: A Case Report. [PDF]

open access: yesClin Case Rep
ABSTRACT Primary localized cutaneous amyloidosis (PCLA) of the vulva is an infrequent diagnosis. Its clinical presentation may mimic neoplastic or inflammatory lesions and could even be associated with human papillomavirus (HPV) of low or high oncogenic risk, making accurate diagnosis and exclusion of systemic involvement essential. A 73‐year‐old woman
Hoegl J   +3 more
europepmc   +2 more sources

Age‐specific melanoma risk associated with nevi: a pooled analysis from the M‐SKIP project

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Objective This study investigates the association of melanoma risk with total‐body nevus count and the presence of atypical nevi in younger (< 40 years) and older (> 60 years) individuals. Methods A pooled analysis was conducted within the M‐SKIP project, based on multiple melanoma case‐control studies.
Giulia Doi   +20 more
wiley   +1 more source

Adherence to Clotting Factor Prophylaxis in Adolescent and Adult Males With Haemophilia

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Clotting factor prophylaxis remains the most prescribed standard‐of‐care treatment for people with haemophilia (PwH). Prophylaxis prevents bleeds, joint damage, and improves quality of life (QoL). Its success depends on treatment adherence, consisting of socioeconomic, behavioural, and disease‐ or therapy‐related factors.
Nathália Martins Beserra   +9 more
wiley   +1 more source

Challenges of Dengue in Hematological Disease Patients: Descriptive Analysis From the DANGO Registry During the 2023–2024 Outbreak in Argentina

open access: yesTransplant Infectious Disease, EarlyView.
During the 2023–2024 Argentine dengue outbreak, 33 patients with hematological disease showed high complication rates, frequent hospitalization (64%), severe thrombocytopenia (90%), and 6% dengue‐attributable mortality. Transfusion‐associated cases were documented.
Gustavo Adolfo Méndez   +16 more
wiley   +1 more source

Evidence and Equity Gaps in Clinical Care of Chronic Lymphocytic Leukaemia in Portugal: A Real‐World, Multicentre, Cohort Study

open access: yeseJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Objectives Targeted therapies have markedly improved outcomes in chronic lymphocytic leukaemia (CLL), particularly among patients with TP53 alterations and unmutated IGHV. However, real‐world studies report persistent inequalities in access to optimal care.
Susana Esteves   +7 more
wiley   +1 more source

Safety and Efficacy of Damoctocog Alfa Pegol in Previously Treated Children Aged 7 to < 12 Years With Severe Haemophilia A in the Phase 3, Open Label Alfa‐PROTECT Main Study

open access: yesEuropean Journal of Haematology, Volume 116, Issue 4, Page 435-442, April 2026.
ABSTRACT Background In the earlier PROTECT VIII Kids study (NCT01775618), damoctocog alfa pegol was efficacious for prevention and treatment of bleeds in children aged < 12 years with severe haemophilia A. Objective Assess the safety of damoctocog alfa pegol, including hypersensitivity and loss of efficacy (LoE) due to an immune response to ...
Margareth C. Ozelo   +13 more
wiley   +1 more source

Experiencia de la prueba de progreso del "National Board of Medical Examiners (NBME)" en la Facultad de Medicina del Colegio de Ciencias de la Salud de la universidad San Francisco de Quito (USFQ) 2006-2011 [PDF]

open access: yes, 2012
A retrospective cohort study was performed; the aim of the study was to analyze the different scores of the National Board of Medical Examiners (NBME) progress test obtained by USFQ medical students between 2006 and 2011, with a total of 484 exams.Se ...
Viteri Estévez, Patricio David
core  

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

open access: yesPediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser   +6 more
wiley   +1 more source

Tecnología, especialismo y sus audiencias. La «Clínica de Leucemias» del Hospital Provincial de Alicante (1953-1960) [PDF]

open access: yes, 2004
La puesta en marcha de una Clínica de Leucemias en el Hospital Provincial de Alicante supuso un revulsivo para el inicio de una actividad investigadora en el marco de un proceso de institucionalización de la especialidad hematológica. El prestigio social
Ballester, Rosa, Perdiguero Gil, Enrique
core   +2 more sources

Prospective validation of podoplanin expression as a diagnostic biomarker of acute promyelocytic leukemia

open access: yesCytometry Part B: Clinical Cytometry, Volume 110, Issue 2, Page 128-133, March 2026.
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva   +7 more
wiley   +1 more source

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