Intensive Chemotherapy With or Without Midostaurin in Adults ≥ 60 Years Old With FLT3-Mutated AML: A FILO-DATAML-PETHEMA Real-World Study. [PDF]
ABSTRACT The addition of midostaurin (MIDO) to intensive chemotherapy (IC) improves survival in younger adults with FLT3‐mutated acute myeloid leukemia (AML); however, real‐world data in elderly patients (≥ 60 years) are limited. This large, retrospective, multicenter study from three European registries (PETHEMA, FILO, DATAML) evaluated MIDO+IC (n ...
Aspas Requena G +31 more
europepmc +2 more sources
Symptomatic Vulvar Primary Cutaneous Amyloidosis Associated With Low-Risk HPV: A Case Report. [PDF]
ABSTRACT Primary localized cutaneous amyloidosis (PCLA) of the vulva is an infrequent diagnosis. Its clinical presentation may mimic neoplastic or inflammatory lesions and could even be associated with human papillomavirus (HPV) of low or high oncogenic risk, making accurate diagnosis and exclusion of systemic involvement essential. A 73‐year‐old woman
Hoegl J +3 more
europepmc +2 more sources
Summary Although adult T‐cell leukaemia/lymphoma (ATL) has a higher burden in certain world regions, outcomes have not been directly compared across regions. We conducted a multicentre cohort study comparing the distribution of ATL subtypes and overall survival (OS) across 1090 adults (≥18 years) diagnosed with ATL during 2000–2023 in Japan (n = 366 ...
Bryan Valcarcel +31 more
wiley +1 more source
Age‐specific melanoma risk associated with nevi: a pooled analysis from the M‐SKIP project
Summary Objective This study investigates the association of melanoma risk with total‐body nevus count and the presence of atypical nevi in younger (< 40 years) and older (> 60 years) individuals. Methods A pooled analysis was conducted within the M‐SKIP project, based on multiple melanoma case‐control studies.
Giulia Doi +20 more
wiley +1 more source
Regional Standardization of CLL Management: Results of a Delphi Consensus Process
ABSTRACT The therapeutic landscape of chronic lymphocytic leukemia (CLL) has been profoundly transformed by the introduction of Bruton tyrosine kinase and BCL‐2 inhibitors. Despite improved survival outcomes, treatment selection remains complex, particularly in older patients with comorbidities, frailty, and increased infectious vulnerability.
Enrica Antonia Martino +22 more
wiley +1 more source
Adherence to Clotting Factor Prophylaxis in Adolescent and Adult Males With Haemophilia
ABSTRACT Introduction Clotting factor prophylaxis remains the most prescribed standard‐of‐care treatment for people with haemophilia (PwH). Prophylaxis prevents bleeds, joint damage, and improves quality of life (QoL). Its success depends on treatment adherence, consisting of socioeconomic, behavioural, and disease‐ or therapy‐related factors.
Nathália Martins Beserra +9 more
wiley +1 more source
Experiencia de la prueba de progreso del "National Board of Medical Examiners (NBME)" en la Facultad de Medicina del Colegio de Ciencias de la Salud de la universidad San Francisco de Quito (USFQ) 2006-2011 [PDF]
A retrospective cohort study was performed; the aim of the study was to analyze the different scores of the National Board of Medical Examiners (NBME) progress test obtained by USFQ medical students between 2006 and 2011, with a total of 484 exams.Se ...
Viteri Estévez, Patricio David
core
Uso de concentrado de hematíes en el Hospital General Universitario de Castellón [PDF]
Treball Final de Grau en Medicina. Codi: MD1158. Curs acadèmic: 2016-2017JUSTIFICACIÓN Y OBJETIVOS: La donación de productos sanguíneos es en un gesto altruista de mucha importancia.
Pérez Bastida, Leire
core
During the 2023–2024 Argentine dengue outbreak, 33 patients with hematological disease showed high complication rates, frequent hospitalization (64%), severe thrombocytopenia (90%), and 6% dengue‐attributable mortality. Transfusion‐associated cases were documented.
Gustavo Adolfo Méndez +16 more
wiley +1 more source
Biología del Sistema Antígeno Leucocitario Humano y su importancia en la Hematología [PDF]
Esta investigación tuvo como objetivo principal describir la biología del sistema antígeno leucocitario humano y su importancia en la hematología, además de determinar la importancia de este sistema característicamente polimórfico e importante en la ...
Balladarez Munguía, Manuel Bernabé +2 more
core

