Results 11 to 20 of about 9,781 (159)

Symptomatic Vulvar Primary Cutaneous Amyloidosis Associated With Low-Risk HPV: A Case Report. [PDF]

open access: yesClin Case Rep
ABSTRACT Primary localized cutaneous amyloidosis (PCLA) of the vulva is an infrequent diagnosis. Its clinical presentation may mimic neoplastic or inflammatory lesions and could even be associated with human papillomavirus (HPV) of low or high oncogenic risk, making accurate diagnosis and exclusion of systemic involvement essential. A 73‐year‐old woman
Hoegl J   +3 more
europepmc   +2 more sources

Hereditary Spherocytosis due to an SPTA1 Nonsense Mutation Coinherited With α spectrin<sup>LELY</sup> in Trans. [PDF]

open access: yesAm J Hematol
American Journal of Hematology, Volume 100, Issue 12, Page 2355-2356, December 2025.
Molina-Arrebola MA, Bain BJ.
europepmc   +2 more sources

Prospective validation of podoplanin expression as a diagnostic biomarker of acute promyelocytic leukemia

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva   +7 more
wiley   +1 more source

Age‐specific melanoma risk associated with nevi: a pooled analysis from the M‐SKIP project

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Objective This study investigates the association of melanoma risk with total‐body nevus count and the presence of atypical nevi in younger (< 40 years) and older (> 60 years) individuals. Methods A pooled analysis was conducted within the M‐SKIP project, based on multiple melanoma case‐control studies.
Giulia Doi   +20 more
wiley   +1 more source

Challenges of Dengue in Hematological Disease Patients: Descriptive Analysis From the DANGO Registry During the 2023–2024 Outbreak in Argentina

open access: yesTransplant Infectious Disease, EarlyView.
During the 2023–2024 Argentine dengue outbreak, 33 patients with hematological disease showed high complication rates, frequent hospitalization (64%), severe thrombocytopenia (90%), and 6% dengue‐attributable mortality. Transfusion‐associated cases were documented.
Gustavo Adolfo Méndez   +16 more
wiley   +1 more source

Safety and Efficacy of Damoctocog Alfa Pegol in Previously Treated Children Aged 7 to < 12 Years With Severe Haemophilia A in the Phase 3, Open Label Alfa‐PROTECT Main Study

open access: yesEuropean Journal of Haematology, Volume 116, Issue 4, Page 435-442, April 2026.
ABSTRACT Background In the earlier PROTECT VIII Kids study (NCT01775618), damoctocog alfa pegol was efficacious for prevention and treatment of bleeds in children aged < 12 years with severe haemophilia A. Objective Assess the safety of damoctocog alfa pegol, including hypersensitivity and loss of efficacy (LoE) due to an immune response to ...
Margareth C. Ozelo   +13 more
wiley   +1 more source

Neurological Peculiarities of POEMS Syndrome: Experience From a Brazilian University Center

open access: yesMuscle &Nerve, Volume 73, Issue 3, Page 421-426, March 2026.
ABSTRACT Aim Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes (POEMS) syndrome is a rare paraneoplastic syndrome associated with significant neurologic morbidity. Better understanding of the manifestations of this disease is crucial to early diagnosis and improvement of prognosis.
Renan Fabri Rosenstein   +5 more
wiley   +1 more source

Avaliação hematológica, bioquimica e ultrassonográfica hepato-renal de caninos submetidos à terapia com Tiocolchicosídeos

open access: yesPubvet, 2018
O tiocolchicosídeo que é um derivado sulfuroso de um glicósido natural de colchicina, utilizado com miorrelaxante por ter ação menos sedativa do que outros relaxantes musculares que atuam sobre o SNC.. Esse medicamento é comumente utilizado no tratamento
Lianna Fernandes Carvalho   +7 more
doaj   +1 more source

Iptacopan for Immune Thrombocytopenia and Cold Agglutinin Disease: A Global Phase 2 Basket Clinical Trial

open access: yesAmerican Journal of Hematology, Volume 101, Issue 2, Page 242-254, February 2026.
ABSTRACT Iptacopan is a first‐in‐class, oral, selective inhibitor of complement factor B that has demonstrated positive efficacy across several complement‐driven diseases. Here we evaluate the efficacy and safety of iptacopan monotherapy in adult patients with primary immune thrombocytopenia (ITP) and primary cold agglutinin disease (CAD). We performed
Alexander Röth   +13 more
wiley   +1 more source

Fatores etários no leucograma de fêmeas zebuínas sadias da raça Nelore (Bos indicus) Influence of age on the leukogram values for healthy Nelore (Zebu) cattle

open access: yesCiência Rural, 2000
Para avaliar-se a influência dos fatores etários sobre o leucograma de fêmeas zebuínas da raça Nelore, examinaram-se amostras de sangue de 158 animais, distribuídos por sete grupos etários ( até 3 meses; 3 a 6 meses; 6 a 12 meses; 12 a 24 meses; 24 a 48 ...
Joselito Nunes Costa   +5 more
doaj   +1 more source

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