Results 41 to 50 of about 218,075 (284)

Recent insights into the role of the microbiome in malignant and benign hematologic diseases [PDF]

, 2021
Growing evidence suggests the impact of microbiome alteration, named dysbiosis, on the development of neoplasms, infections, inflammatory diseases, and immuno-mediated disorders.
Fattizzo B., Folino F., Barcellini W., Cavallaro F.   +3 more
core   +1 more source

Secondary Neoplasm in Survivors of Childhood Hematological Malignancies—Systematic Review

Children
Background: Childhood cancers account for approximately 1–2% of all malignancies worldwide, with hematologic cancers representing about 35–40% of pediatric cases.
Ioana-Alexandra Horneț, Andreea Bianca Stoica, Dora Mihaela Cîmpian, Lucian Puşcaşiu   +3 more
doaj   +1 more source

Differences between the oral changes presented by patients with solid and hematologic tumors during the chemotherapeutic treatment [PDF]

Journal of Applied Oral Science, 2019
Objective: This study sought to identify the differences between the oral changes presented by patients with solid and hematologic tumors during chemotherapeutic treatment.
Isabella Lima Arrais Ribeiro, Sâmara Munique Silva, Rebecca Rhuanny Tolentino Limeira, Paulo Rogério Ferreti Bonan, Ana Maria Gondim Valença, Eufrásio Andrade de Lima Neto, Ricardo Dias de Castro   +6 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Clinical molecular testing for ASXL1 c.1934dupG p.Gly646fs mutation in hematologic neoplasms in the NGS era. [PDF]

PLoS One, 2018
ASXL1 (additional sex combs like 1) is a gene that is mutated in a number of hematological neoplasms. The most common genetic alteration is c.1934dupG p.Gly646fs.
Montes-Moreno S, Routbort MJ, Lohman EJ, Barkoh BA, Kanagal-Shamanna R, Bueso-Ramos CE, Singh RR, Medeiros LJ, Luthra R, Patel KP.   +9 more
europepmc   +3 more sources

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia [PDF]

, 2022
Myeloid neoplasms and acute leukemias derive from the clonal expansion of hematopoietic cells driven by somatic gene mutations. Although assessment of morphology plays a crucial role in the diagnostic evaluation of patients with these malignancies ...
Cargo, Catherine A, Komrokji, Rami, Arber, Daniel A, Ogawa, Seishi, Garcia-Manero, Guillermo, Kim, Annette S, Brown, Anna L, Berliner, Nancy, Duncavage, Eric J, Ross, David M, Patel, Keyur P, Orazi, Attilio, Savona, Michael, Haferlach, Torsten, Loghavi, Sanam, Malcovati, Luca, Iacobucci, Ilaria, Lee-Cheun Loh, Mignon, Solé, Francesc, DiNardo, Courtney D, Shimamura, Akiko, Reiter, Andreas, Wu, David, Falini, Brunangelo, Klco, Jeffery M, Papaemmanuil, Elli, Arcila, Maria E, Skoda, Radek C, Bagg, Adam, Hasserjian, Robert P, Tefferi, Ayalew, Jaiswal, Siddhartha, Bejar, Rafael, Walter, Matthew J, Cazzola, Mario, Hellström-Lindberg, Eva, Ebert, Benjamin L, Döhner, Hartmut, Vannucchi, Alessandro M, Godley, Lucy A, Branford, Susan, Borowitz, Michael J, Stone, Richard M, Mullighan, Charles G, Iacobucci, I, Godley, LA, Patel, KP, Malcovati, L, Jaiswal, S, Bagg, A, Hasserjian, RP, Vannucchi, AM, Duncavage, EJ, DiNardo, CD   +53 more
core   +1 more source

Cost of the treatment of myelodisplastic syndrome in Brazil

Revista Brasileira de Hematologia e Hemoterapia, 2011
INTRODUCTION: Myelodysplastic syndrome is an incurable and rare hematological disease that affects the production of blood cells. One aim of treatment is to maintain the blood-cell count to near-normal levels.
Otávio Clark, Enéas José de Matos Faleiros   +1 more
doaj   +1 more source