Results 221 to 230 of about 479,621 (361)

Long non-coding RNA MALAT1 in hematological malignancies and its clinical applications

Chunlan Zhang, Yun Qin, Yu Wu, Heng Xu, Yang Shu   +4 more
openalex   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Differentiating Alcohol and Substance Use Disorders Using Multiclass Machine Learning Models Based on Routine Hemogram Parameters. [PDF]

Healthcare (Basel)
Asaf A, Ogur YS, Erdoğan Kaya A, Kızılaslan O, Tunçkal M, Erdoğan Aktürk B, Yazla E.   +6 more
europepmc   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Demographic and hematological differences between endometriosis and menorrhagia in Saudi women: A retrospective observational study of 946 patients. [PDF]

Medicine (Baltimore)
Abdulwahed AM, Alanazi F, Farzan R, Alqahtani MM, Al-Sharafa MM, Alselmi TF, Alasiri G, Shahbaz RH, Alanazi NT, Alanazi M, Souleymane M.   +10 more
europepmc   +1 more source

Hematological abnormalities in newborn infants with down syndrome

, 1983
Marvin E. Miller, Janice M. Cosgriff, John M. Opitz   +2 more
openalex   +2 more sources

Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice [PDF]

, 2018
Richard Coffey, Ugo Sardo, Léon Kautz, Victoria Gabayan, Elizabeta Nemeth, Tomas Ganz   +5 more
openalex   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Spontaneous atraumatic pediatric basal ganglia hemorrhage in the setting of COLGALT1-related collagenopathy: illustrative case. [PDF]

J Neurosurg Case Lessons
Chaisson JM, Darden DL, Adesina AE, Guillen Arguello R, Haastrup MO, Ponce Mejia L, Roberts O.   +6 more
europepmc   +1 more source

Incidence of hematologic malignancies and mortality associated with GLP-1 receptor agonist and SGLT2 inhibitor use in type 2 diabetes mellitus: results of a retrospective cohort study of electronic health records

Eric E. Irons, Keri Ann Pfeil, Jaime A. Pérez, Koen van Besien   +3 more
openalex   +1 more source