Results 241 to 250 of about 479,621 (361)

Screening for leptospirosis in clinically suspected cases [PDF]

, 2010
Behaeghel, Isabelle, Butaye, Patrick, Goossens, Els, Hansen, Pascale, Meroc, Estelle, Roels, Stefan   +5 more
core  

Genetic, clinical, and biochemical profiling of Gilbert syndrome in a Nepali cohort: High prevalence of the UGT1A1 c.-3279T>G polymorphism and correlation with hematological parameters. [PDF]

PLoS One
Ghimire PG, Ghimire P, Pande R.
europepmc   +1 more source

Fundamental research on Antibody-Drug Conjugates and their applications in solid tumors and hematologic malignancies

Shu Sun
openalex   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

The role of epigenetic modifications in hematological cancers. [PDF]

Front Oncol
Ilic J, Bold A, Knop S.
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Mutational signatures in hematological malignancies. [PDF]

Einstein (Sao Paulo)
Sartori FA, Pontes JVP, Campregher PV, LaFramboise T.   +3 more
europepmc   +1 more source

Nucleated red blood cells: A hematological indicator of perinatal stress and neonatal risk [PDF]

Harshita KM, Sumitha Ram MP, Shashikala K, Anisha TS   +3 more
openalex   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Pernicious Anemia Resulting in Intramedullary Hemolysis, Masking Underlying Polycythemia Vera and Mild Alpha-Thalassemia-A Case Report. [PDF]

Case Rep Hematol
Rohner A, Schnegg-Kaufmann AS, Banz Y, Rosenstock P.   +3 more
europepmc   +1 more source