Results 261 to 270 of about 479,621 (361)

SUN-205 Beyond Hypoglycemia: Type I Glycogen Storage Disease with Endocrine, Hematologic, and Renal Involvement [PDF]

María Fernanda Rivera-López, María del Carmen Burguete Bojalil, Mercedes Aguilar-Soto, Francisco J. Gómez‐Pérez, Jose Alfredo Puentes-López   +4 more
openalex   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

Establishment and Temporal Validation of Next-Generation Reference Intervals for Routine Hematological Parameters Using Large-Scale Data. [PDF]

Diagnostics (Basel)
Ma C, Guan L, Chen Q, Cheng R, Wu W, Qiu L.   +5 more
europepmc   +1 more source

DEVELOPMENT OF MEASUREMENT GUIDELINES INCORPORATING A CORE OUTCOME SET (COS) FOR STUDIES ON REHABILITATIVE INTERVENTIONS IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES TREATED WITH ALLOGENEIC STEM CELL TRANSPLANTATION: A DELPHI STUDY

Anastasios Manettas, Lidwine B. Mokkink, Erik Aerts, Andriyana K. Bankova, Ramona Engst, Nicola Greco, Panagiotis V. Tsaklis   +6 more
openalex   +2 more sources

Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy

Advanced Science, EarlyView.
An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang, Wei‐Tong Chen, Yu‐Ying Shen, Zhao‐Yang Wang, Kai Li, Xueli Zhao, Yanjuan Sang, Xiaoyuan Chen, Shuang‐Quan Zang   +8 more
wiley   +1 more source

Integrated Functional and Histopathological Modulation of Chronic Thioacetamide-Induced Liver Fibrosis by Mesenchymal Stem Cell Therapy in a Preclinical Model. [PDF]

Diseases
Prado ABR, Lozano LL, Diaz Obregón DZ, Carbajal Zegarra VH, De León Delgado J, Pando Mayta JW, Carrasco AGM, Yparraguirre Salcedo KG, Ramirez Atencio CW.   +8 more
europepmc   +1 more source

A Comparative Analysis of Hematological Inflammatory Markers in Stable and Exacerbated Bronchial Asthma

Balaji Ayeratharasu Rajasekharan, Yachana Mageshwaran, Thamilmani Somasundaram, Suresh Sagadevan, Muthukumaran Lakshmanan, Rathinam Sridhar, Meenakshi Narasimhan   +6 more
openalex   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Safety evaluation of an effervescent curcuminoids-ascorbic acid-polysaccharide-β-cyclodextrin (CUR-A-Poly-β-CD) inclusion complex powder in healthy volunteers: A non-placebo-controlled pilot study. [PDF]

Toxicol Rep
Pramvichai C, Mongkolwat W, Aluksanasuwan S, Jaidee W, Charoensup R, Pimtong S, Chearmuangphan B, Rongjumnong A, Wanta A, Morchang A, Somsuan K.   +10 more
europepmc   +1 more source

BCR::ABL1‐Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B‐ALL Cells to Enhancer‐Targeting Drugs

Advanced Science, EarlyView.
Ng et al. show that the BCR::ABL1 kinase that drives the lymphoid leukemia Ph+B‐ALL modulates enhancer function by coopting signaling‐inducible transcription factors such as MYC, STAT5, and ETV5. BCR::ABL1 thereby promotes the transcriptional program driving and defining this leukemia and renders Ph+B‐ALL cells hypersensitive to enhancer‐inhibiting ...
Han Leng Ng, Trudy Lee Glaser, Jintao Zhu, Mark E. Robinson, Kadriye N. Cosgun, Valeriya Malysheva, Ozgen Deniz, Nicholas T. Crump, Kaiyue Helian, Andrew J. Innes, Richard Burt, Li Sun, George John, Haibin Zhou, Atsunori Kaneshige, Longchuan Bai, Shaomeng Wang, Mikhail Spivakov, Markus Müschen, Niklas Feldhahn   +19 more
wiley   +1 more source