Results 111 to 120 of about 591,468 (262)
مدیریت اطلاعات سلامت, 2009 Introduction: Hematology section provides valuable information for diagnosis and treatment of patients to improve the health of them. In this regard Hematology Information System led to deliver produced information accurately and timely.
Farkhondeh Asadi +2 more
doaj
The administration of PD-1 and PD-L1 inhibitors in pediatric hematology: a literature review
Педиатрическая фармакологияThe discovery of immune checkpoints (IC) has become a landmark event in immuno-oncolog y, improving the understanding of the mechanisms of tumor cells evading immune sur veillance.
Aleksandra S. Paderina, Timur T. Valiev
doaj +1 more source
The Blood Ontology: An ontology in the domain of hematology [PDF]
, 2011 Despite the importance of human blood to clinical practice and research, hematology and blood transfusion data remain scattered throughout a range of disparate sources.
Barcellos, Almeida Mauricio +3 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Jurnal Pembangunan dan Alam Lestari, 2015 This research has the objectives to determine LC50 96 hours value and observation toward hematology, gills and kidney histology of goldfish (Cyprinus carpio) exposed to organophosphate pesticide with Poksim active compound (trade brand FOKKER 500 EC ...
Dewi Nur Setyorini +2 more
doaj
216 Jewish Hospital of St. Louis [PDF]
, 1986 https://digitalcommons.wustl.edu/bjc_216/1180/thumbnail ...
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
216 Jewish Hospital of St. Louis [PDF]
, 1985 https://digitalcommons.wustl.edu/bjc_216/1176/thumbnail ...
core +1 more source