Results 91 to 100 of about 591,468 (262)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Danish National Lymphoma Registry

Clinical Epidemiology, 2016
Bente Arboe,1 Pär Josefsson,2 Judit Jørgensen,3 Jacob Haaber,4 Paw Jensen,5 Christian Poulsen,6 Dorthe Rønnov-Jessen,7 Robert S Pedersen,8 Per Pedersen,9 Mikael Frederiksen,10 Michael Pedersen,1 Peter de Nully Brown1 1Department of ...
Arboe B, Josefsson P, Jørgensen J, Haaber J, Jensen P, Poulsen C, Rønnov-Jessen D, Pedersen RS, Pedersen P, Frederiksen M, Pedersen M, de Nully Brown P   +11 more
doaj  

Perbandingan Kadar Hemoglobin Menggunakan POCT (Point Care Of Testing) dengan Alat Hematology Analyzer Pada Pasien Normal dan Anemia

Jurnal Ilmiah Kesehatan
Di laboratorium pemeriksaan hemoglobin merupakan salah satu pemeriksaan skrining, penggunaan alat bervariasi salah satunya adalah menggunakan POCT. Alasan penggunaan alat ini karena  lebih efisien dibanding hematology analyzer, seperti pengerjaannya ...
Anggi Fauzi, Arina Novilla, Nining Ratna Ningrum, Iis Herawati   +3 more
doaj   +1 more source

Nivolumab plus ipilimumab in the treatment of advanced melanoma. [PDF]

, 2015
Advanced melanoma has historically been a difficult disease to treat due to few effective systemic treatment options. However, over the past few years, scientific advancements in immune checkpoint inhibition have resulted in several novel approaches that
Daud, Adil I, Tsai, Katy K
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The Effect of Ambient Temperature, Relative Humidity, and Temperature–Humidity Index on Stress Hormone and Inflammatory Response in Exercising Adult Standardbred Horses

Animals
In the present study, the changes in the markers of stress and inflammatory responses of 12 Standardbred horses were investigated before and after exercise during late spring and summer.
Francesca Arfuso, Maria Rizzo, Laura Perillo, Federica Arrigo, Elisabetta Giudice, Giuseppe Piccione, Caterina Faggio, Vincenzo Monteverde   +7 more
doaj   +1 more source

In Vivo Renal Clearance, Biodistribution, Toxicity of Gold nanoclusters

, 2012
Gold nanoparticles have shown great prospective in cancer diagnosis and therapy, but they can not be metabolized and prefer to accumulate in liver and spleen due to their large size.
Fan, Fei-Yue, Fan, Sai-Jun, Liu, Pei-Xun, Shen, Xiu, Wu, Di, Zhang, Xiao-Dong   +5 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Suspected Permethrin-Containing Powder Bath Poisoning in a Flock of Mountain Quail (Oreortyx pictus)

Animals
Generally, birds are less sensitive to pyrethrins and pyrethroids compared to mammals; however, suspected permethrin toxicosis was fatal in seven mountain quails (Oreortyx pictus) treated with a permethrin-containing powder bath.
János Gál, Miklós Marosán, Míra Mándoki, Lilla Dénes, Miklós Süth, Dániel Pleva, József Lehel   +6 more
doaj   +1 more source