Results 141 to 150 of about 461,852 (357)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Vyacheslav Viktorovich Novitsky (to the 60th birthday)
Бюллетень сибирской медицины, 2006 Creative biography of the prominent Russian scientist — the rector and the chief of pathophysiology chair of the Siberian State Medical University (Tomsk), honoured scientist of RF, academician of RAMS, professor Vyacheslav Victorovich Novitsky is ...
Editorial Article
doaj
Blood parameters and hepatic histopathology of broilers fed rations supplemented with essential oils
Revista Brasileira de ZootecniaThis study aimed to evaluate the hematological profile, hepatic function, and histopathology of mixed-sex broilers fed rations supplemented with microencapsulated essential oils from Cymbopogon flexuosus (lemon grass) and Lippia rotundifolia (chá-de ...
Vanessa Kelly Ferreira do Rosário Santos +7 more
doaj +1 more source
NIDDK Announcement: Resources and Funding Available for Research in Nonmalignant Hematology
, 2017 Terry Rogers Bishop
openalex +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Retracted: Plasmablastic Lymphoma: A Review of Current Knowledge and Future Directions
Advances in Hematology, 2016 Advances in Hematology
doaj +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Evaluation of Clinical Pharmacist’s Interventions in Hematology
, 2020 Ji Seon Yoo +4 more
openalex +2 more sources