Results 191 to 200 of about 575,997 (353)

Discovery of a Potent and Selective TEAD Degrader with Durable Degradation Activity

Advanced Science, EarlyView.
KG‐FP‐003, a highly potent TEAD‐YAP PROTAC derived from the patented inhibitor is developed. It selectively degrades endogenous TEAD proteins in HiBiT systems without IMiD‐related off‐target effects. Screening across 867 cancer cell lines revealed broad and superior anti‐tumor activity, highlighting its therapeutic potential through targeted TEAD ...
Linhui Cao, Jing Yang, Yuhang Liu, Xiaotong Chen, Yufang Shi, Yunshuo Zhao, Yong Zhang, Jian Chen, Bowen Li, Wuqiang Wen, Lu Chen, Bo Peng, Lu Huang, Yanli Sun, Lixin Zhou, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Zhixiang Guo, Jing Xing, Guangya Zhu, Yazhou Wang, Baishan Jiang, Jing Lu, Kehao Zhao, Wenchao Lu   +25 more
wiley   +1 more source

Hematology clinicopathological exercise

Iraqi Journal of Hematology, 2016
Asmaa Mohammed Thanun
doaj   +1 more source

Burnout symptoms among hematology professionals: An EHA survey. [PDF]

Hemasphere
Bommier C, Perolla A, Zelić Kerep A, Irimia R, Iatrou N, Macintyre E, Borges N, EHA Burnout Survey Initiative.   +7 more
europepmc   +1 more source

Book Review: Progress in Hematology, Volume V

, 1968
G. Hamilton Fairley
openalex   +1 more source

AMERICAN SOCIETY OF HEMATOLOGY Sixteenth Annual Meeting • Chicago, Illinois • December 1-4, 1973 [PDF]

, 1973
Antigens Baker, Pam R. Taub, Crises Kraus, James J. Corrigan, Christina Pagel, Transport Cation, Stephen A. Feig, Paul O. Dutcher, Hepatomas Glew, R Pinkard, Sara Peters   +10 more
openalex   +1 more source

Improved survival after acute graft-versus-host disease diagnosis in the modern era [PDF]

, 2017
et al.,, Hayashi, Robert J, Vig, Ravi
core   +1 more source

Histone Lactylation‐Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells

Advanced Science, EarlyView.
Glioblastoma (GBM) is the most aggressive primary brain tumor, with glioma stem cells (GSCs) driving treatment resistance. This study reveals that lactate promotes histone lactylation (H3K18la) at the VRK1 promoter, regulating GSC stemness and proliferation via the H3K18la/VRK1/YBX1/SOX2 pathway. The VRK1‐targeted nanoliposome A/TMZ‐siVRK1 demonstrates
Jinna Li, Chenyue Tang, Xuefeng Zhang, Rui Xing, Qing Guo   +4 more
wiley   +1 more source

Asciminib for relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia. [PDF]

Blood Adv
Chanut M, Cabannes-Hamy A, Balsat M, Sahki N, Raffoux E, Hicheri Y, Lioure B, Laemmel L, Leguay T, Cacheux V, Gallego-Hernanz MP, Pieragostini A, Roth-Guepin G, Gabellier L, Denizon N, Willems L, Cabrera Q, Chantepie S, Coiteux V, Capdupuy C, Carré M, Machet A, Lambert J, Roux S, Nicolini FE, Boissel N, Clappier E, Kim R, Rousselot P.   +28 more
europepmc   +1 more source

The Application of An Electronic Particle Counter with A Mean Cell Volume Computer and An Hematocrit Accessory to Avian Hematology

, 1977
Ellen G. Steel, H. D. Petersen, Albert Blanks, Harry E. Smalley   +3 more
openalex   +1 more source

AMERICAN SOCIETY OF HEMATOLOGY Seventeenth Annual Meeting • Atlanta, Georgia • December 7-10, 1974 [PDF]

, 1974
Bensusen Harris, J Saauels, AJ Adamson, C. Julian Rosenthal, W.A. Andes, Gwen Rogers, Stomatocytosis Wiley   +6 more
openalex   +1 more source