Results 231 to 240 of about 461,852 (357)

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

Advanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J. Rosenwasser, Iain E. Dunlop, Derfogail Delcassian   +5 more
wiley   +1 more source

PiP‐Plex: A Particle‐in‐Particle System for Multiplexed Quantification of Proteins Secreted by Single Cells

Advanced Materials, EarlyView.
Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier, Byeong‐Ui Moon, Mojra Janta‐Polczynski, Yonatan Morocz, Fabian Svahn, Molly Shen, Ljuboje Lukic, Lidija Malic, Teodor Veres, Andy Ng, David Juncker   +10 more
wiley   +1 more source

Outcome of patients with mantle cell lymphoma after failure of anti-CD19 CAR T-cell therapy: a DESCAR-T study by LYSA Group. [PDF]

Blood Adv
Aymard M, Cheminant M, Houot R, Cuozzo A, Gat E, Thieblemont C, Ricard L, Roulin L, Bouabdallah K, Safar V, Guidez S, Fayard A, Brisou G, Ysebaert L, Hermine O, Tessoulin B, Herbaux C, Le Gouill S, Sarkozy C.   +18 more
europepmc   +1 more source

Hematology Advocacy Doesn’t Skip a Beat With New Congress and Administration

, 2021
ASH Staff
openalex   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Mucosal-Associated Lymphoid Tissue Lymphoma in Southeast Asia: A 15-Year Retrospective Multicenter Study. [PDF]

Hematol Rep
Prayongratana K, Thamgrang T, Laoruangroj C, Norasetthada L, Rattanathammethee T, Bunworasate U, Wudhikarn K, Julamanee J, Noiperm P, Chuncharunee S, Niparuck P, Khuhapinant A, Siritanaratkul N, Kanya P, Chansung K, Sirijerachai C, Jit-Uaekul D, Chaloemwong J, Kanitsap N, Wong P, Makruasi N, Wongkhantee S, Suwanban T, Intragumtornchai T.   +23 more
europepmc   +1 more source

Knowledge of Patients Undergoing Chemotherapy toward Self Care in Kirkuk Center for Oncology and Hematology

Ahmed Atia Ali, Rebaz Ismael Ali
openalex   +2 more sources

Spider Silk–Integrated Biomimetic Micropillars With Dual Adhesion for Improved Wound Hemostasis and Healing

Advanced Materials Technologies, EarlyView.
The patch mimics the dual physicochemical adhesion mechanisms of gecko toe micropillars and spider silk proteins, enabling strong interfacial bonding via partially cured micropillars. Its facile fabrication allows customization for precision medicine, while its motion responsiveness offers potential for real‐time wound monitoring.
Chengxin Luan, Meng Wei, Xinran Chen, Ni Gan, Bingbing Gao   +4 more
wiley   +1 more source

Author Correction: Microbiota-reprogrammed phosphatidylcholine inactivates cytotoxic CD8 T cells through UFMylation via exosomal SerpinB9 in multiple myeloma. [PDF]

Nat Commun
Yan W, Shi X, Zhao Y, Liu X, Jia X, Gao L, Yuan J, Liao A, Yasui H, Wang X, Wang X, Zhang R, Wang H.   +12 more
europepmc   +1 more source

Food‐Based Edible Wireless Sensing Device with Isotropic Electromagnetic Response for Gastrointestinal Monitoring

Advanced Materials Technologies, EarlyView.
A sensor is fabricated that reflects electromagnetic waves wirelessly using only edible materials. The substrate is made of edible materials such as sugar and starch, and the electrodes are made of gold. This sensor has isotropic electromagnetic wave characteristics in response to rotation.
Ryosuke Matsuda, Kentaro Tomita, Shion Miura, Michiyuki Satoh, Tetsuo Kan, Hiroaki Onoe   +5 more
wiley   +1 more source