Results 221 to 230 of about 591,468 (262)

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

Advanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang, Xiaoyan Yin, Ting Wang, Hongfu Zhao, Zhipeng Zhao, Jinbao Wang, Cheng Tao, Xuanchu Ge, Yanze Li, Linlin Liu, Fuxin Xue   +10 more
wiley   +1 more source

Correction: Danzero et al. An Automated Cartridge-Based Microfluidic System for Real-Time Quantification of <i>BCR::ABL1</i> Transcripts in Chronic Myeloid Leukemia: An Italian Experience. <i>Int. J. Mol. Sci.</i> 2025, <i>26</i>, 8932. [PDF]

Int J Mol Sci
Danzero AC, Gottardi EM, Quarantelli F, Del Prete C, Potenza A, Venturi C, Berchialla P, Guerrini F, Bono C, Ottaviani E, Galimberti S, Fava C, Izzo B.   +12 more
europepmc   +1 more source

The AUTACE That Degrades KRAS and Engages CD8+ T Cells for the Treatment of KRAS/TP53 Co‐Mutant Tumors

Advanced Science, EarlyView.
AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li, Bolin Li, Yanan Hao, Bo Pang, Pan Li, Chunli Li, Yu Tang   +6 more
wiley   +1 more source

Influence of different therapy strategies in patients with myelodysplastic neoplasms (MDS) on overall survival with regard to different decades: data from the German MDS registry. [PDF]

Ann Hematol
Welsch J, Schulz F, Kasprzak A, Aul C, Götze KS, Nusch A, Lipke J, Parmentier S, Strupp C, Nachtkamp K, Kobbe G, Dietrich S, Gattermann N, Germing U.   +13 more
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Nutritional Management in Patients With Hematological Malignancies: An Underestimated Supportive Care Issue. [PDF]

Cureus
El Ouafa Y, Fadi M, Benrahma H, Bouanani N.   +3 more
europepmc   +1 more source

Brentuximab vedotin with chemotherapy for stage III or IV Hodgkin\u27s lymphoma [PDF]

, 2018
Bartlett, N. L, et al,
core   +1 more source

A Dual‐Responsive Versatile Nanohybrid Orchestrating Tumor Elimination and Tumor‐Associated Osteolysis Restoration via Sequential Release

Advanced Science, EarlyView.
The versatile CaO2@CuMOF@HAP nanohybrid demonstrates an outstanding MMP9/pH‐triggered release performance for sequential release of osteogenic growth peptide into deep‐seated tumor‐infiltrated bone destruction areas and dual ions into tumor cells, enabling efficient tumor‐associated osteolysis restoration and tumor elimination for more comprehensive ...
Lan Liu, Han‐Zhe Liu, Zhe‐Nan Liu, Tong Wang, Li‐Li Yu, Qiu‐Jing Li, Zi‐Yi Chen, Guo‐Feng Luo, Zheng‐Jun Shang   +8 more
wiley   +1 more source

Sustained remission after discontinuation of ALK inhibition in ALK-positive histiocytosis. [PDF]

Blood Cancer J
Kemps PG, Picarsic JL, Héritier S, Donadieu J, Haroche J, Farnault L, Gaspari S, Evseev DA, Osipova DS, Druy AE, Minkov M, Picton S, Beilken A, Möhle R, Kuzmanović MB, Okuma HS, Chow CW, Campbell MA, Phillips GS, Zhou Y, Goyal G, Go RS, Yeo KK, Sisk BA, Weinstein JL, Campbell PK, Diamond EL, Emile JF.   +27 more
europepmc   +1 more source

Nature‐Inspired Surface Modification Strategy Reverses the Autophagic Flux Impairment of Mitochondrial Transplantation for Attenuating Ischemic Strokes

Advanced Science, EarlyView.
The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang, Qiyang Ding, Lei Shi, Ji Xia, Shuyue Zhang, Chenxin Jian, Yixiao Yan, Xiuhua Luo, Jiarui Wang, Ming Cheng, Yiqiong Jia, Hao Tian, Wei Gao   +12 more
wiley   +1 more source