Results 231 to 240 of about 478,042 (312)

Implementing Instagram as educational tool for teaching hematology and medical oncology - a cross-sectional study. [PDF]

BMC Med Educ
Altmann E, Hübner J, Bauer-Büntzel C, Büntzel J.   +3 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Long-term MAPK inhibition of childhood refractory-Langerhans cell histiocytosis: an observational study of 288 patients. [PDF]

Blood Adv
Donadieu J, Evseev D, Pegoraro F, Sieni E, Slater O, Hutter C, Astigarraga I, Lehrnbecher T, van den Bos C, Simonin M, Ahlmann M, Barkaoui M, Le Louet S, Chevallier A, Chalard F, Nguyen T, Holzhauer S, Beutel K, Haenicke H, Escherich G, Garcia-Obregon S, Valero-Arrese L, Ruano D, Moreno MA, Habes D, Lacaille F, McLin V, Bomken S, Bishop H, Penn A, Naeije L, Kabbara N, Milne P, Hélias-Rodzewicz Z, Kolenova A, Renard C, Berard PM, Thalhammer J, Pagnier A, Salmon A, Aladjidi N, Olivier L, Saultier P, Blanc L, Gandemer V, Schneider P, Hessissen L, Golan M, Elitzur S, Ben Arush M, Lustig DA, Dvir R, Raciborska A, Malas Z, Diallo S, Levy G, Efremova V, Munthe-Kaas MC, von Bahr Greenwood T, Felizzia G, Braier J, Boudiaf H, Ben Fraj I, Svojgr K, Krenova Z, Bernard F, Adam C, Karaoli E, Kristensen IA, Dahl C, Trambusti I, Gaspari S, De Fusco C, Chiaravalli S, Corti P, Todesco A, Papadakis V, Luz I, Costa V, Osipova D, Lyudovskikh E, Maschan M, Bronin G, Burcev E, Idbaih A, Larabi IA, Bellouard M, Alvarez JC, Novosad O, Collin M, Henter JI, Emile JF, Héritier S, Minkov M.   +93 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Ropeginterferon alfa-2b-njft treatment in essential thrombocythemia across different driver mutations: results from a North American, single-arm, multicentre study (EXCEED-ET). [PDF]

Lancet Reg Health Am
Reeves BN, El Chaer F, Foltz L, Tashi T, Abu-Zeinah G, Qin A, Lucas J, Halpern AB, Maze D, Safah H, O'Connell CL, Goel S, Rein L, Fang B, How J, Babu S, Li Z, Cerquozzi S, Oh ST, Hunter AM, Podoltsev N, Vachhani P, Cunningham JM, Hillis C, Bose P, Yacoub A, Mascarenhas J, Zagrijtschuk O, Castro H, Mesa RA, Masarova L.   +30 more
europepmc   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Hematology in times of crisis: Lessons learned and strategic priorities from the EHA-ASH Joint Workshop on Ukraine. [PDF]

Hemasphere
Istomin O, Yakimkova T, Belkhedim R, Bolaños N, Döhner K, Ganser A, Haferlach T, Ilbawi A, Kacharian A, Kizyma R, Klymenko S, Korenkova S, Leebeek F, Lysytsia O, Medvediev B, Mlynarski W, Niederwieser D, Nogovitsyna Y, Rondelli D, Selina I, Usenko G, Shokun N, Heyman M, Niemeyer C, Müller A.   +24 more
europepmc   +1 more source

Understanding the impact of social determinants of health in hematology: a scoping review of trends across journals and over time. [PDF]

Blood Adv
Lu B, Troyer J, Krause KJ, Lapite A, Aviles M, Della-Moretta S, Dobson D, Farrokhi K, Hasanali ZS, Pillai P, Taborda C, Villagomez L, Vo PT, Wang'ondu RW, Yui JC, Weyand AC, Fingrut WB.   +16 more
europepmc   +1 more source

Refining favorable-risk classification in pediatric <i>RUNX1::RUNX1T1</i> acute myeloid leukemia. [PDF]

Blood Sci
Zhang X.
europepmc   +1 more source