BHLHE40 Cooperates with GATA2/3 to Control Human Syncytiotrophoblast Lineage Differentiation
BHLHE40 interacts directly with GATA2 and GATA3 and co‐occupies genomic loci critical for STB differentiation and function. BHLHE40 also affects GATA2/3 binding at enhancer and promoter regions. Moreover, BHLHE40 is potentially involved in genome‐wide remodeling of H3K4me3 and H3K27ac chromatin landscapes through GATA2/3 recruitment, activating ...
Lijin Peng +11 more
wiley +1 more source
Prognostic impacts of marital status and other socioeconomic factors in patients with chronic lymphocytic leukemia: an analysis of SEER database. [PDF]
Zhang J +6 more
europepmc +1 more source
The impact of the graft-versus-leukemia effect on survival in acute lymphoblastic leukemia [PDF]
et al,, Uy, Geoffrey, Yeshurun, Moshe
core +1 more source
CDSCs exhibit the potential to differentiate into endothelial cells, vascular pericytes, and osteoblasts. These differentiated cells are capable of secreting additional pro‐hematopoietic cytokines. Furthermore, CDSCs can inhibit apoptosis and reduce DNA damage in injured hematopoietic stem and progenitor cells (HSPCs, including RHSCs and RHPCs), while ...
Rui Dong +16 more
wiley +1 more source
ggalign: Bridging the Grammar of Graphics and Biological Multilayered Complexity
The ggalign package provides a comprehensive framework for composable visualization built on top of ggplot2. Its primary purpose is to enable the construction of complex multi‐plot layouts with consistent observation alignment across plots, particularly for high‐dimensional data contexts such as genomics, transcriptomics, and microbiome studies ...
Yun Peng +9 more
wiley +1 more source
Commentary on: A Comprehensive Mechanical and Chemoprophylaxis Algorithm for Prevention of Venous Thromboembolism in Lipoabdominoplasty. [PDF]
Pannucci CJ.
europepmc +1 more source
Targeting HDAC and PARP Enhances STING‐Dependent Antitumor Immunity in STING‐Deficient Tumor
Dual HDAC and PARP inhibition restores STING signaling, enhances interferon response, and boosts antitumor immunity in STING‐deficient tumors. . Abstract The stimulator of interferon genes (STING)‐mediated innate immune pathway plays an important role in tumor immunosurveillance.
Chengzhou Mao +10 more
wiley +1 more source
Late-Onset Veno-Occlusive Disease (VOD) Post Haploidentical Transplant: A Diagnostic Challenge Requiring Liver Biopsy- A Case Report. [PDF]
Trehan M +5 more
europepmc +1 more source
Sex, sport, and body-size dependency of hematology in highly trained athletes
Richard D. Telford, Ross B. Cunningham
openalex +1 more source
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao +14 more
wiley +1 more source

