Results 261 to 270 of about 461,852 (357)
Correction: Genetic polymorphisms in cGAS-STING-mediated type I interferon innate immune signaling pathway are associated with DLBCL. [PDF]
Front ImmunolZhou Q, Jia R, Chen J, Tan Y, Ma Y, Luan M, Sheng X, Han X, Li S, Lu F, Ji C, Wang D, Ye J. +12 moreeuropepmc +1 more sourceThree‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy
Advanced Science, EarlyView.Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract
The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.Yao Lin, Xiong Sun, Chengguo Li, Ming Yang, Ke Wu, Ke Liu, Anshu Li, Xiaoming Shuai, Kailin Cai, Zheng Wang, Guobin Wang, Peng Zhang, Jianfeng Shen, Kaixiong Tao, Yuping Yin +14 morewiley +1 more sourceAcute Promyelocytic Leukemia with double minute chromosomes: a rare case with high relapse risk. [PDF]
Oxf Med Case ReportsSasaki Y, Shimada S, Kawamata N, Hayashi H, Nagao K, Kuroiwa K, Narita H, Okamura R, Watanuki M, Arai N, Yanagisawa K, Hattori N. +11 moreeuropepmc +1 more sourceProcyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway
Advanced Science, EarlyView.A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang +8 morewiley +1 more sourceNew Technologies and Digital Health Tools in Patients With Solid Tumors and Hematological Malignancies: Cross-Sectional Multicenter Survey Study.
JMIR CancerLopez-Garcia A, Diaz-Aizpun C, Gallego-Diaz B, Miranda-Castillo C, Yuste-Platero M, Beltran-Alvarez P, Carames-Sanchez C, Garcia-Foncillas J, Llamas-Sillero P, Del Olmo-Rodriguez M, Short-Apellaniz J, Pfang B, Arcos-Campillo J, Cordoba R. +13 moreeuropepmc +1 more sourceSingle‐Cell Dissection Reveals Immune Dysregulation After CD5 or CD7‐Directed Chimeric Antigen Receptor T‐Cell Therapy
Advanced Science, EarlyView.Single‐cell RNA/TCR/BCR sequencing reveals that 5CAR therapy in T‐ALL induces T‐cell exhaustion, reduces EBV‐associated TCRs, lowers TCR/BCR diversity, and increases NK/DC/monocyte activation and function. In contrast, 7CAR therapy reduces multiple pathogen‐associated TCRs, enhances NK cell activation and function, decreases monocyte activation, and ...Yuechen Luo, Haixiao Zhang, Kaiting Tang, Yiming Wang, Huajiang Dong, Wei Qi, Lingling Shan, Yue Tan, Liping Zhao, Jun Shi, Erlie Jiang, Jing Pan, Xiaoming Feng +12 morewiley +1 more sourceEffectiveness of Gilteritinib Beyond Second-Line Therapy in Relapsed/Refractory FLT3 -Mutated Acute Myeloid Leukemia: A Real-World Multicenter Study of 171 Patients. [PDF]
Am J HematolMolica M, Miralles G, Dillon R, Annunziata M, Basheer F, Bergua JM, Calmet FV, Campbell V, Cetin D, Cimino G, Ciotti G, Corbingi A, De Fazio L, Erol HA, Federico V, Gil C, Mutlu YG, Malcorra AB, Mariani S, Mazzone C, Mulè A, Musuraca G, Khan A, Norata M, O'Nions J, Palumbo FE, Papayannidis C, Piccioni AL, Rubio MTO, Sanchez-Tovar J, Serin I, Serrao A, Sevindik OG, Sucato G, Urbano MA, Vetro C, Vives S, Rossi M, Martelli MP, Montesinos P, Othman J, Perrone S. +41 moreeuropepmc +1 more source